Cremaffin Plus
Cremaffin Plus is a syrup made by Abbott that contains Liquid paraffin + Magnesium hydroxide + Sodium picosulfate. It combines Liquid paraffin: lubricant laxative, Magnesium hydroxide: antacid and laxative and Sodium picosulfate: stimulant laxative.
| Ingredient (salt) | Amount |
|---|---|
| Liquid paraffin | see pack |
| Magnesium hydroxide | see pack |
| Sodium picosulfate | see pack |
Liquid paraffin
What it is used for
Softens and lubricates stools to relieve constipation.
How it works
A mineral oil that coats and softens stool so it passes more easily.
How to take it
Take as directed, not just before lying down. Not for regular long-term use.
Common side effects
- Oily leakage from the back passage
- Itching around the anus
Get medical help straight away if
Coughing or breathing trouble after a dose (oil can be breathed in)
Be careful
Not for long-term use; avoid lying down right after taking it.
Other medicines and interactions
Long use reduces absorption of vitamins A, D, E and K.
Pregnancy and breastfeeding
Avoid in pregnancy; other laxatives are preferred.
Magnesium hydroxide
What it is used for
Neutralises acid; in larger amounts it softens stools.
How it works
An antacid that neutralises acid; in larger doses it draws water into the bowel and works as a laxative (milk of magnesia).
How to take it
As an antacid, after meals and at bedtime. As a laxative, 30 to 45 ml at bedtime with water. Keep 2 hours apart from other medicines.
Common side effects
- Diarrhoea
- Stomach cramps
Get medical help straight away if
Muscle weakness, slow heartbeat or drowsiness (too much magnesium, especially with kidney disease)
Be careful
Can cause loose motions; caution with kidney disease.
Other medicines and interactions
Reduces absorption of iron, ciprofloxacin, tetracyclines, levothyroxine and some other medicines; separate doses by at least 2 hours.
Pregnancy and breastfeeding
Short-term use is considered acceptable in pregnancy and breastfeeding.
Sodium picosulfate
What it is used for
Relieves constipation.
How it works
A stimulant laxative activated by gut bacteria in the large bowel; it works in 6 to 12 hours. Large doses are used to empty the bowel before a colonoscopy.
How to take it
For constipation, 5 to 10 mg at bedtime. For bowel preparation, follow the clinic's instructions exactly and drink the extra fluids.
Common side effects
- Stomach cramps
- Diarrhoea
- Nausea
Get medical help straight away if
- Dizziness, confusion or very little urine (dehydration after bowel prep)
- Severe pain
Be careful
Short-term use only; can cause cramps.
Other medicines and interactions
Antibiotics can reduce its effect. Long use can lower potassium.
Pregnancy and breastfeeding
Ask a doctor before using in pregnancy; generally acceptable while breastfeeding.
Common questions
What is Cremaffin Plus?
Cremaffin Plus is a syrup by Abbott containing Liquid paraffin + Magnesium hydroxide + Sodium picosulfate.
What is Cremaffin Plus used for?
Softens and lubricates stools to relieve constipation. Neutralises acid; in larger amounts it softens stools. Relieves constipation.
How should I take Cremaffin Plus?
Take as directed, not just before lying down. Not for regular long-term use. As an antacid, after meals and at bedtime. As a laxative, 30 to 45 ml at bedtime with water. Keep 2 hours apart from other medicines. For constipation, 5 to 10 mg at bedtime. For bowel preparation, follow the clinic's instructions exactly and drink the extra fluids. Always follow the dose your doctor or the pack gives.
What are the side effects of Cremaffin Plus?
Common side effects include: Oily leakage from the back passage, itching around the anus, Diarrhoea, stomach cramps, Stomach cramps, diarrhoea, nausea. Get medical help straight away for: Coughing or breathing trouble after a dose (oil can be breathed in), Muscle weakness, slow heartbeat or drowsiness (too much magnesium, especially with kidney disease), Dizziness, confusion or very little urine (dehydration after bowel prep), severe pain.
Does Cremaffin Plus need a prescription?
It is usually sold without a prescription in India, but ask a pharmacist if you take other medicines or have a long-term illness.
Can I take Cremaffin Plus in pregnancy or while breastfeeding?
Avoid in pregnancy; other laxatives are preferred. Short-term use is considered acceptable in pregnancy and breastfeeding. Ask a doctor before using in pregnancy; generally acceptable while breastfeeding.
What are the substitutes for Cremaffin Plus?
We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.
Sources and further reading
- Liquid paraffin: NHS · MedlinePlus
- Magnesium hydroxide: NHS · MedlinePlus
- Sodium picosulfate: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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