Glizid-M
Glizid-M is a tablet made by Panacea Biotec that contains Gliclazide 80 mg + Metformin 500 mg. It combines Gliclazide: diabetes medicine (sulfonylurea) and Metformin: diabetes medicine (biguanide).
| Ingredient (salt) | Amount |
|---|---|
| Gliclazide | 80 mg |
| Metformin | 500 mg |
Gliclazide
What it is used for
Lowers blood sugar by making the pancreas release more insulin.
How it works
A sulfonylurea that makes the pancreas release more insulin.
How to take it
Usually 40 to 160 mg with breakfast (or twice daily); slow-release 30 to 120 mg once a day with breakfast. Do not skip meals.
Common side effects
- Low blood sugar
- Weight gain
- Stomach upset
Get medical help straight away if
Low blood sugar: shaking, sweating, hunger, confusion or fainting (take 15 g of sugar such as glucose or juice, then food)
Be careful
Can cause low sugar; do not skip meals.
Other medicines and interactions
Low sugar more likely with alcohol, fluconazole, clarithromycin and other diabetes medicines; beta blockers can hide signs.
Pregnancy and breastfeeding
Usually switched to insulin in pregnancy; not recommended while breastfeeding.
Metformin
What it is used for
Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.
How it works
The usual first medicine for type 2 diabetes. It lowers the amount of sugar the liver releases and helps the body respond to insulin. On its own it rarely causes low blood sugar and does not cause weight gain.
How to take it
Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop.
Common side effects
- Diarrhoea
- Nausea
- Stomach pain
- Metallic taste
- Reduced appetite
Get medical help straight away if
- Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis)
- Tingling feet or tiredness after years of use (low vitamin B12)
Be careful
Take with food; can cause stomach upset. Stop before scans with contrast or surgery if told.
Other medicines and interactions
Doctors pause it before scans with iodine contrast and before major surgery, and during dehydrating illness (vomiting, diarrhoea). Heavy alcohol raises lactic acidosis risk.
Pregnancy and breastfeeding
Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.
Common questions
What is Glizid-M?
Glizid-M is a tablet by Panacea Biotec containing Gliclazide 80 mg + Metformin 500 mg.
What is Glizid-M used for?
Lowers blood sugar by making the pancreas release more insulin. Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.
How should I take Glizid-M?
Usually 40 to 160 mg with breakfast (or twice daily); slow-release 30 to 120 mg once a day with breakfast. Do not skip meals. Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop. Always follow the dose your doctor or the pack gives.
What are the side effects of Glizid-M?
Common side effects include: Low blood sugar, weight gain, stomach upset, Diarrhoea, nausea, stomach pain, metallic taste, reduced appetite. Get medical help straight away for: Low blood sugar: shaking, sweating, hunger, confusion or fainting (take 15 g of sugar such as glucose or juice, then food), Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis), tingling feet or tiredness after years of use (low vitamin B12).
Does Glizid-M need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Glizid-M in pregnancy or while breastfeeding?
Usually switched to insulin in pregnancy; not recommended while breastfeeding. Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.
What are the substitutes for Glizid-M?
We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.
Sources and further reading
- Gliclazide: NHS · MedlinePlus
- Metformin: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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