Ibuclin
Ibuclin is a tablet made by Dr. Reddy's that contains Ibuprofen 400 mg + Paracetamol 325 mg. It combines Ibuprofen: anti-inflammatory painkiller (nsaid) and Paracetamol: pain reliever and fever reducer.
| Ingredient (salt) | Amount |
|---|---|
| Ibuprofen | 400 mg |
| Paracetamol | 325 mg |
Ibuprofen
What it is used for
Relieves pain, swelling and fever, for example from sprains, period pain, toothache and arthritis.
How it works
It blocks COX enzymes that make prostaglandins, the chemicals that cause pain, swelling and fever.
How to take it
Adults usually take 200 to 400 mg three times a day with or after food, up to 1,200 mg a day without a prescription. Use the lowest dose for the shortest time.
Common side effects
- Stomach upset
- Heartburn
- Nausea
- Indigestion
- Headache
- Dizziness
Get medical help straight away if
- Black or bloody stools or vomiting blood
- Severe stomach pain
- Wheezing or breathlessness (it can trigger asthma)
- Swelling of the face or a severe rash
- Passing much less urine
Be careful
Take after food. Can irritate the stomach; not for people with ulcers, kidney disease or late pregnancy without medical advice.
Other medicines and interactions
Do not combine with other NSAIDs such as aspirin, diclofenac or naproxen. It raises bleeding risk with warfarin, clopidogrel and SSRIs, and can reduce the effect of blood pressure medicines and harm the kidneys when taken with ACE inhibitors, ARBs or diuretics.
Pregnancy and breastfeeding
Avoid from 20 weeks of pregnancy onward unless a doctor advises it, as it can affect the baby's kidneys and heart; ask before using earlier in pregnancy. Small amounts pass into breast milk and short courses are generally considered compatible with breastfeeding.
Paracetamol
What it is used for
Brings down fever and eases mild to moderate pain such as headache, body ache and toothache.
How it works
It works in the brain to raise the pain threshold and acts on the body's temperature centre to bring a fever down. Unlike NSAIDs it has little effect on swelling and is gentle on the stomach.
How to take it
Usual adult dose is 500 mg to 1 g every 4 to 6 hours, no more than 4 g (for example eight 500 mg tablets) in 24 hours; lower if you weigh under 50 kg, drink alcohol regularly or have liver disease. Children's doses go by weight. It can be taken with or without food.
Common side effects
- Side effects are rare at normal doses
- Occasionally rash or nausea
Get medical help straight away if
- You took more than the maximum dose, even if you feel well (liver damage shows up only after 1 to 3 days)
- Yellow skin or eyes
- A rash with blistering
Be careful
Too much damages the liver. Many cold and pain medicines also contain it, so avoid taking two at once; avoid with heavy alcohol use.
Other medicines and interactions
Many cold, flu and combination painkillers already contain paracetamol, so check every label to avoid a double dose. Regular high use can strengthen the effect of warfarin. Heavy alcohol use raises the risk of liver damage.
Pregnancy and breastfeeding
Paracetamol is the usual first choice for pain and fever in pregnancy and while breastfeeding, at the lowest dose that works for the shortest time.
Same composition, other brands (9)
Ask your doctor or pharmacist before switching brands.
Common questions
What is Ibuclin?
Ibuclin is a tablet by Dr. Reddy's containing Ibuprofen 400 mg + Paracetamol 325 mg.
What is Ibuclin used for?
Relieves pain, swelling and fever, for example from sprains, period pain, toothache and arthritis. Brings down fever and eases mild to moderate pain such as headache, body ache and toothache.
How should I take Ibuclin?
Adults usually take 200 to 400 mg three times a day with or after food, up to 1,200 mg a day without a prescription. Use the lowest dose for the shortest time. Usual adult dose is 500 mg to 1 g every 4 to 6 hours, no more than 4 g (for example eight 500 mg tablets) in 24 hours; lower if you weigh under 50 kg, drink alcohol regularly or have liver disease. Children's doses go by weight. It can be taken with or without food. Always follow the dose your doctor or the pack gives.
What are the side effects of Ibuclin?
Common side effects include: Stomach upset, heartburn, nausea, indigestion, headache, dizziness, Side effects are rare at normal doses, occasionally rash or nausea. Get medical help straight away for: Black or bloody stools or vomiting blood, severe stomach pain, wheezing or breathlessness (it can trigger asthma), swelling of the face or a severe rash, passing much less urine, You took more than the maximum dose, even if you feel well (liver damage shows up only after 1 to 3 days), yellow skin or eyes, a rash with blistering.
Does Ibuclin need a prescription?
It is usually sold without a prescription in India, but ask a pharmacist if you take other medicines or have a long-term illness.
Can I take Ibuclin in pregnancy or while breastfeeding?
Avoid from 20 weeks of pregnancy onward unless a doctor advises it, as it can affect the baby's kidneys and heart; ask before using earlier in pregnancy. Small amounts pass into breast milk and short courses are generally considered compatible with breastfeeding. Paracetamol is the usual first choice for pain and fever in pregnancy and while breastfeeding, at the lowest dose that works for the shortest time.
What are the substitutes for Ibuclin?
Brands with the same composition: Combiflam, Ibugesic Plus, Flexon, Brufamol, Brustan, Brufen P, Flexib 325, Ibuflamar P, Fenceta 325. Ask your doctor or pharmacist before switching.
Sources and further reading
- Ibuprofen: NHS · MedlinePlus
- Paracetamol: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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