Jalra-M 50/500
Jalra-M 50/500 is a tablet made by USV that contains Vildagliptin 50 mg + Metformin 500 mg. It combines Vildagliptin: diabetes medicine (dpp-4 inhibitor) and Metformin: diabetes medicine (biguanide).
| Ingredient (salt) | Amount |
|---|---|
| Vildagliptin | 50 mg |
| Metformin | 500 mg |
Vildagliptin
What it is used for
Helps the body release insulin after meals to lower blood sugar.
How it works
A DPP-4 inhibitor (gliptin) that increases insulin after meals and lowers glucagon.
How to take it
Usually 50 mg twice a day, or once a day with a sulfonylurea. Liver tests are checked.
Common side effects
- Headache
- Stuffy nose or sore throat
- Joint pain
- Dizziness
Get medical help straight away if
- Severe stomach pain spreading to the back (pancreatitis)
- Blistering skin (bullous pemphigoid)
- Allergic swelling
- Yellow skin
Be careful
Liver tests may be needed.
Other medicines and interactions
Low blood sugar is more likely when combined with sulfonylureas or insulin.
Pregnancy and breastfeeding
Not recommended in pregnancy or while breastfeeding; insulin is preferred.
Metformin
What it is used for
Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.
How it works
The usual first medicine for type 2 diabetes. It lowers the amount of sugar the liver releases and helps the body respond to insulin. On its own it rarely causes low blood sugar and does not cause weight gain.
How to take it
Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop.
Common side effects
- Diarrhoea
- Nausea
- Stomach pain
- Metallic taste
- Reduced appetite
Get medical help straight away if
- Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis)
- Tingling feet or tiredness after years of use (low vitamin B12)
Be careful
Take with food; can cause stomach upset. Stop before scans with contrast or surgery if told.
Other medicines and interactions
Doctors pause it before scans with iodine contrast and before major surgery, and during dehydrating illness (vomiting, diarrhoea). Heavy alcohol raises lactic acidosis risk.
Pregnancy and breastfeeding
Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.
Same composition, other brands (2)
Ask your doctor or pharmacist before switching brands.
Same ingredients, different strength or form
Common questions
What is Jalra-M 50/500?
Jalra-M 50/500 is a tablet by USV containing Vildagliptin 50 mg + Metformin 500 mg.
What is Jalra-M 50/500 used for?
Helps the body release insulin after meals to lower blood sugar. Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.
How should I take Jalra-M 50/500?
Usually 50 mg twice a day, or once a day with a sulfonylurea. Liver tests are checked. Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop. Always follow the dose your doctor or the pack gives.
What are the side effects of Jalra-M 50/500?
Common side effects include: Headache, stuffy nose or sore throat, joint pain, dizziness, Diarrhoea, nausea, stomach pain, metallic taste, reduced appetite. Get medical help straight away for: Severe stomach pain spreading to the back (pancreatitis), blistering skin (bullous pemphigoid), allergic swelling, yellow skin, Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis), tingling feet or tiredness after years of use (low vitamin B12).
Does Jalra-M 50/500 need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Jalra-M 50/500 in pregnancy or while breastfeeding?
Not recommended in pregnancy or while breastfeeding; insulin is preferred. Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.
What are the substitutes for Jalra-M 50/500?
Brands with the same composition: Galvus Met 50/500, Zomelis Met 50/500. Ask your doctor or pharmacist before switching.
Sources and further reading
- Vildagliptin: NHS · MedlinePlus
- Metformin: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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