Januvia 100

Tablet · MSD
PRESCRIPTION MEDICINE

Januvia 100 is a tablet made by MSD that contains Sitagliptin 100 mg. Sitagliptin is a diabetes medicine (dpp-4 inhibitor): helps the body release insulin after meals to lower blood sugar.

Ingredient (salt)Amount
Sitagliptin100 mg

What it is used for

Helps the body release insulin after meals to lower blood sugar.

How it works

A DPP-4 inhibitor (gliptin). It boosts the gut hormones that tell the pancreas to release insulin after meals, and rarely causes low sugar on its own.

How to take it

Usually 100 mg once a day, with or without food; lower doses for kidney disease.

Common side effects

  • Headache
  • Stuffy nose or sore throat
  • Joint pain

Get medical help straight away if

  • Severe stomach pain spreading to the back (pancreatitis)
  • Blistering skin (bullous pemphigoid)
  • Allergic swelling

Be careful

Report severe stomach pain (rarely pancreatitis).

Other medicines and interactions

Low blood sugar is more likely when combined with sulfonylureas or insulin.

Pregnancy and breastfeeding

Not recommended in pregnancy or while breastfeeding; insulin is preferred.

Same composition, other brands (1)

Ask your doctor or pharmacist before switching brands.

Same ingredients, different strength or form

Common questions

What is Januvia 100?

Januvia 100 is a tablet by MSD containing Sitagliptin 100 mg.

What is Januvia 100 used for?

Helps the body release insulin after meals to lower blood sugar.

How should I take Januvia 100?

Usually 100 mg once a day, with or without food; lower doses for kidney disease. Always follow the dose your doctor or the pack gives.

What are the side effects of Januvia 100?

Common side effects include: Headache, stuffy nose or sore throat, joint pain. Get medical help straight away for: Severe stomach pain spreading to the back (pancreatitis), blistering skin (bullous pemphigoid), allergic swelling.

Does Januvia 100 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Januvia 100 in pregnancy or while breastfeeding?

Not recommended in pregnancy or while breastfeeding; insulin is preferred.

What are the substitutes for Januvia 100?

Brands with the same composition: Istavel 100. Ask your doctor or pharmacist before switching.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.