Oflox 400

Tablet · Cipla
PRESCRIPTION MEDICINE

Oflox 400 is a tablet made by Cipla that contains Ofloxacin 400 mg. Ofloxacin is a antibiotic (fluoroquinolone): treats urine, gut, chest and some ear and eye infections.

Ingredient (salt)Amount
Ofloxacin400 mg

What it is used for

Treats urine, gut, chest and some ear and eye infections.

How it works

A fluoroquinolone antibiotic, also used as ear and eye drops, often combined with ornidazole for gut infections.

How to take it

Tablets usually 200 to 400 mg twice a day. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise.

Common side effects

  • Nausea
  • Diarrhoea
  • Dizziness
  • Trouble sleeping

Get medical help straight away if

  • Tendon pain or swelling, especially the heel (stop and rest)
  • Tingling, numbness or burning in the hands or feet
  • Mood changes or confusion
  • Severe diarrhoea
  • Palpitations

Be careful

Can rarely damage tendons and nerves; avoid antacids at the same time.

Other medicines and interactions

Antacids, iron, zinc, calcium and milk taken at the same time block absorption; separate by at least 2 hours before or 6 hours after. Raises tendon risk with steroids. Can affect warfarin, diabetes medicines (blood sugar swings) and heart rhythm medicines.

Pregnancy and breastfeeding

Usually avoided in pregnancy and while breastfeeding unless no other antibiotic will work.

Same ingredients, different strength or form

Common questions

What is Oflox 400?

Oflox 400 is a tablet by Cipla containing Ofloxacin 400 mg.

What is Oflox 400 used for?

Treats urine, gut, chest and some ear and eye infections.

How should I take Oflox 400?

Tablets usually 200 to 400 mg twice a day. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise. Always follow the dose your doctor or the pack gives.

What are the side effects of Oflox 400?

Common side effects include: Nausea, diarrhoea, dizziness, trouble sleeping. Get medical help straight away for: Tendon pain or swelling, especially the heel (stop and rest), tingling, numbness or burning in the hands or feet, mood changes or confusion, severe diarrhoea, palpitations.

Does Oflox 400 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Oflox 400 in pregnancy or while breastfeeding?

Usually avoided in pregnancy and while breastfeeding unless no other antibiotic will work.

What are the substitutes for Oflox 400?

We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.