Ondem Injection

Injection · Alkem
PRESCRIPTION MEDICINE

Ondem Injection is a injection made by Alkem that contains Ondansetron 2 mg per ml. Ondansetron is a anti-vomiting: prevents and treats nausea and vomiting.

Ingredient (salt)Amount
Ondansetron2 mg per ml

What it is used for

Prevents and treats nausea and vomiting.

How it works

It blocks serotonin (5-HT3) receptors in the gut and brain that trigger vomiting. Widely used for vomiting from stomach bugs, chemotherapy and surgery.

How to take it

Usually 4 to 8 mg up to two or three times a day; dissolving tablets melt on the tongue. Children's doses go by weight.

Common side effects

  • Headache
  • Constipation
  • Feeling of warmth or flushing
  • Tiredness

Get medical help straight away if

  • Fast or irregular heartbeat or fainting
  • Agitation, fever and shaking (serotonin syndrome)
  • Allergic swelling

Be careful

Can cause constipation or headache.

Other medicines and interactions

Risk of heart rhythm problems with other QT-prolonging medicines. Serotonin syndrome risk with SSRIs, SNRIs and tramadol. Do not take with apomorphine.

Pregnancy and breastfeeding

Doctors may use it in pregnancy for severe vomiting after weighing a small possible risk in the first three months. Considered acceptable while breastfeeding.

Same composition, other brands (1)

Ask your doctor or pharmacist before switching brands.

Same ingredients, different strength or form

Common questions

What is Ondem Injection?

Ondem Injection is a injection by Alkem containing Ondansetron 2 mg per ml.

What is Ondem Injection used for?

Prevents and treats nausea and vomiting.

How should I take Ondem Injection?

Usually 4 to 8 mg up to two or three times a day; dissolving tablets melt on the tongue. Children's doses go by weight. Always follow the dose your doctor or the pack gives.

What are the side effects of Ondem Injection?

Common side effects include: Headache, constipation, feeling of warmth or flushing, tiredness. Get medical help straight away for: Fast or irregular heartbeat or fainting, agitation, fever and shaking (serotonin syndrome), allergic swelling.

Does Ondem Injection need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Ondem Injection in pregnancy or while breastfeeding?

Doctors may use it in pregnancy for severe vomiting after weighing a small possible risk in the first three months. Considered acceptable while breastfeeding.

What are the substitutes for Ondem Injection?

Brands with the same composition: Emeset Injection. Ask your doctor or pharmacist before switching.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.