Oxramet XR 10/500

Tablet · Sun Pharma
PRESCRIPTION MEDICINE

Oxramet XR 10/500 is a tablet made by Sun Pharma that contains Dapagliflozin 10 mg + Metformin 500 mg (slow release). It combines Dapagliflozin: diabetes medicine (sglt2 inhibitor) and Metformin: diabetes medicine (biguanide).

Ingredient (salt)Amount
Dapagliflozin10 mg
Metformin500 mg (slow release)

Dapagliflozin

Diabetes medicine (SGLT2 inhibitor)

What it is used for

Lowers blood sugar by passing extra sugar out in urine; also used in heart and kidney failure.

How it works

An SGLT2 inhibitor (gliflozin) that removes sugar through the urine and protects the heart and kidneys.

How to take it

Usually 10 mg once a day, with or without food.

Common side effects

  • Genital thrush
  • Urinary infections
  • Passing more urine
  • Thirst

Get medical help straight away if

  • Feeling very unwell with nausea, vomiting, stomach pain and fast breathing, even with normal sugar (ketoacidosis)
  • Pain, redness or swelling of the genitals or area behind them
  • Dizziness on standing

Be careful

Drink enough water; can cause genital fungal infections.

Other medicines and interactions

Adds to the effect of diuretics (dehydration). Low sugar more likely with insulin or sulfonylureas. Doctors pause it before surgery and during illness with poor eating.

Pregnancy and breastfeeding

Not recommended in pregnancy or while breastfeeding.

Metformin

Diabetes medicine (biguanide)

What it is used for

Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.

How it works

The usual first medicine for type 2 diabetes. It lowers the amount of sugar the liver releases and helps the body respond to insulin. On its own it rarely causes low blood sugar and does not cause weight gain.

How to take it

Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop.

Common side effects

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Metallic taste
  • Reduced appetite

Get medical help straight away if

  • Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis)
  • Tingling feet or tiredness after years of use (low vitamin B12)

Be careful

Take with food; can cause stomach upset. Stop before scans with contrast or surgery if told.

Other medicines and interactions

Doctors pause it before scans with iodine contrast and before major surgery, and during dehydrating illness (vomiting, diarrhoea). Heavy alcohol raises lactic acidosis risk.

Pregnancy and breastfeeding

Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.

Same composition, other brands (1)

Xigduo XR 10/500

Ask your doctor or pharmacist before switching brands.

Common questions

What is Oxramet XR 10/500?

Oxramet XR 10/500 is a tablet by Sun Pharma containing Dapagliflozin 10 mg + Metformin 500 mg (slow release).

What is Oxramet XR 10/500 used for?

Lowers blood sugar by passing extra sugar out in urine; also used in heart and kidney failure. Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.

How should I take Oxramet XR 10/500?

Usually 10 mg once a day, with or without food. Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop. Always follow the dose your doctor or the pack gives.

What are the side effects of Oxramet XR 10/500?

Common side effects include: Genital thrush, urinary infections, passing more urine, thirst, Diarrhoea, nausea, stomach pain, metallic taste, reduced appetite. Get medical help straight away for: Feeling very unwell with nausea, vomiting, stomach pain and fast breathing, even with normal sugar (ketoacidosis), pain, redness or swelling of the genitals or area behind them, dizziness on standing, Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis), tingling feet or tiredness after years of use (low vitamin B12).

Does Oxramet XR 10/500 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Oxramet XR 10/500 in pregnancy or while breastfeeding?

Not recommended in pregnancy or while breastfeeding. Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.

What are the substitutes for Oxramet XR 10/500?

Brands with the same composition: Xigduo XR 10/500. Ask your doctor or pharmacist before switching.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.