Repace-H
Repace-H is a tablet made by Sun Pharma that contains Losartan 50 mg + Hydrochlorothiazide 12.5 mg. It combines Losartan: blood pressure medicine (arb) and Hydrochlorothiazide: diuretic (water pill).
| Ingredient (salt) | Amount |
|---|---|
| Losartan | 50 mg |
| Hydrochlorothiazide | 12.5 mg |
Losartan
What it is used for
Lowers blood pressure and protects the kidneys in diabetes.
How it works
An angiotensin receptor blocker (ARB) for high blood pressure, heart failure and diabetic kidney disease. It also lowers uric acid slightly.
How to take it
Usually 25 to 100 mg once a day.
Common side effects
- Dizziness, especially when standing up
- Tiredness
- Raised potassium
Get medical help straight away if
- Swelling of the face, lips or tongue
- Fainting
- Much less urine
- Muscle weakness or irregular heartbeat (high potassium)
Be careful
Not in pregnancy. Can raise potassium.
Other medicines and interactions
Potassium supplements, salt substitutes, spironolactone and NSAIDs raise potassium and kidney risk. Do not combine with an ACE inhibitor or aliskiren. Raises lithium levels.
Pregnancy and breastfeeding
Must not be used in pregnancy (it harms the baby's kidneys); switch before trying to conceive. Ask your doctor about breastfeeding; other medicines may be preferred.
Hydrochlorothiazide
What it is used for
Lowers blood pressure by removing extra salt and water.
How it works
A thiazide diuretic (water pill) that makes the kidneys pass more salt and water, lowering blood pressure. Often combined with an ARB.
How to take it
Usually 12.5 to 25 mg once a day in the morning so you are not up at night.
Common side effects
- Passing more urine
- Dizziness
- Low potassium or sodium
- Raised sugar or uric acid
- Sensitivity to sunlight
Get medical help straight away if
- Muscle cramps or weakness, confusion (salt imbalance)
- Gout attack
- Sudden eye pain or blurred vision
Be careful
More urination; can lower potassium or raise sugar and uric acid.
Other medicines and interactions
Raises lithium levels. Low potassium is more likely with steroids and laxatives. NSAIDs weaken it.
Pregnancy and breastfeeding
Usually avoided in pregnancy; can reduce milk supply at high doses.
Same composition, other brands (1)
Ask your doctor or pharmacist before switching brands.
Common questions
What is Repace-H?
Repace-H is a tablet by Sun Pharma containing Losartan 50 mg + Hydrochlorothiazide 12.5 mg.
What is Repace-H used for?
Lowers blood pressure and protects the kidneys in diabetes. Lowers blood pressure by removing extra salt and water.
How should I take Repace-H?
Usually 25 to 100 mg once a day. Usually 12.5 to 25 mg once a day in the morning so you are not up at night. Always follow the dose your doctor or the pack gives.
What are the side effects of Repace-H?
Common side effects include: Dizziness, especially when standing up, tiredness, raised potassium, Passing more urine, dizziness, low potassium or sodium, raised sugar or uric acid, sensitivity to sunlight. Get medical help straight away for: Swelling of the face, lips or tongue, fainting, much less urine, muscle weakness or irregular heartbeat (high potassium), Muscle cramps or weakness, confusion (salt imbalance), gout attack, sudden eye pain or blurred vision.
Does Repace-H need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Repace-H in pregnancy or while breastfeeding?
Must not be used in pregnancy (it harms the baby's kidneys); switch before trying to conceive. Ask your doctor about breastfeeding; other medicines may be preferred. Usually avoided in pregnancy; can reduce milk supply at high doses.
What are the substitutes for Repace-H?
Brands with the same composition: Losar-H. Ask your doctor or pharmacist before switching.
Sources and further reading
- Losartan: NHS · MedlinePlus
- Hydrochlorothiazide: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
🔎 Search another medicine