Seroflo

Inhaler/rotacap · Cipla
PRESCRIPTION MEDICINE

Seroflo is a inhaler/rotacap made by Cipla that contains Salmeterol + Fluticasone. It combines Salmeterol: long-acting bronchodilator and Fluticasone: steroid (inhaled or nasal).

Ingredient (salt)Amount
Salmeterolsee pack
Fluticasonesee pack

Salmeterol

Long-acting bronchodilator

What it is used for

Keeps the airways open for many hours in asthma and COPD.

How it works

A long-acting bronchodilator (LABA) lasting about 12 hours, combined with fluticasone in asthma and COPD inhalers.

How to take it

Usually 1 or 2 puffs twice daily, every day. It is not for quick relief; keep a salbutamol inhaler for that. Never use a LABA alone for asthma.

Common side effects

  • Headache
  • Tremor
  • Palpitations
  • Muscle cramps

Get medical help straight away if

  • Sudden worsening of breathing after use
  • Chest pain

Be careful

Used with a steroid inhaler for asthma, not on its own.

Other medicines and interactions

Ketoconazole, itraconazole, clarithromycin and ritonavir raise its level and heart effects. Beta blockers may block it.

Pregnancy and breastfeeding

Can be continued in pregnancy and breastfeeding if needed; uncontrolled asthma is the bigger risk.

Fluticasone

Steroid (inhaled or nasal)

What it is used for

Reduces airway or nasal inflammation in asthma and allergies.

How it works

A potent steroid used as an inhaler to prevent asthma and COPD flares, or as a nasal spray for allergic rhinitis.

How to take it

Inhaler: every day as prescribed, rinse mouth after use. Nasal spray: 1 to 2 sprays per nostril once daily, aiming slightly outwards; it takes a few days for full effect.

Common side effects

  • Hoarseness
  • Oral thrush
  • Sore throat
  • Nosebleeds (nasal spray)
  • Headache

Get medical help straight away if

  • White patches in the mouth
  • Frequent nosebleeds
  • Blurred vision

Be careful

Rinse your mouth after inhaler use.

Other medicines and interactions

Ritonavir, cobicistat, itraconazole and ketoconazole can raise its level enough to cause steroid side effects.

Pregnancy and breastfeeding

Inhaled and nasal forms are generally considered acceptable in pregnancy and breastfeeding when needed.

Common questions

What is Seroflo?

Seroflo is a inhaler/rotacap by Cipla containing Salmeterol + Fluticasone.

What is Seroflo used for?

Keeps the airways open for many hours in asthma and COPD. Reduces airway or nasal inflammation in asthma and allergies.

How should I take Seroflo?

Usually 1 or 2 puffs twice daily, every day. It is not for quick relief; keep a salbutamol inhaler for that. Never use a LABA alone for asthma. Inhaler: every day as prescribed, rinse mouth after use. Nasal spray: 1 to 2 sprays per nostril once daily, aiming slightly outwards; it takes a few days for full effect. Always follow the dose your doctor or the pack gives.

What are the side effects of Seroflo?

Common side effects include: Headache, tremor, palpitations, muscle cramps, Hoarseness, oral thrush, sore throat, nosebleeds (nasal spray), headache. Get medical help straight away for: Sudden worsening of breathing after use, chest pain, White patches in the mouth, frequent nosebleeds, blurred vision.

Does Seroflo need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Seroflo in pregnancy or while breastfeeding?

Can be continued in pregnancy and breastfeeding if needed; uncontrolled asthma is the bigger risk. Inhaled and nasal forms are generally considered acceptable in pregnancy and breastfeeding when needed.

What are the substitutes for Seroflo?

We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.