Siphene 50

Tablet · Serum Institute
PRESCRIPTION MEDICINE

Siphene 50 is a tablet made by Serum Institute that contains Clomiphene 50 mg. Clomiphene is a fertility medicine: helps the ovaries release an egg in women who do not ovulate regularly.

Ingredient (salt)Amount
Clomiphene50 mg

What it is used for

Helps the ovaries release an egg in women who do not ovulate regularly.

How it works

A fertility medicine that triggers ovulation by making the brain release more ovary-stimulating hormones.

How to take it

Usually 50 mg a day for 5 days from day 2 to 5 of the cycle, with monitoring; no more than 6 cycles.

Common side effects

  • Hot flushes
  • Bloating
  • Mood swings
  • Visual blurring

Get medical help straight away if

  • Severe tummy pain or swelling (ovarian overstimulation)
  • Visual disturbance (stop)

Be careful

Use only under a doctor's monitoring; can cause twins.

Other medicines and interactions

Few drug interactions.

Pregnancy and breastfeeding

Stop once pregnant; not for use while breastfeeding.

Same composition, other brands (1)

Ask your doctor or pharmacist before switching brands.

Same ingredients, different strength or form

Common questions

What is Siphene 50?

Siphene 50 is a tablet by Serum Institute containing Clomiphene 50 mg.

What is Siphene 50 used for?

Helps the ovaries release an egg in women who do not ovulate regularly.

How should I take Siphene 50?

Usually 50 mg a day for 5 days from day 2 to 5 of the cycle, with monitoring; no more than 6 cycles. Always follow the dose your doctor or the pack gives.

What are the side effects of Siphene 50?

Common side effects include: Hot flushes, bloating, mood swings, visual blurring. Get medical help straight away for: Severe tummy pain or swelling (ovarian overstimulation), visual disturbance (stop).

Does Siphene 50 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Siphene 50 in pregnancy or while breastfeeding?

Stop once pregnant; not for use while breastfeeding.

What are the substitutes for Siphene 50?

Brands with the same composition: Fertomid 50. Ask your doctor or pharmacist before switching.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.