Spasmofirst
Spasmofirst is a tablet made by Wockhardt that contains Mefenamic acid 250 mg + Dicyclomine 10 mg. It combines Mefenamic acid: anti-inflammatory painkiller (nsaid) and Dicyclomine: antispasmodic.
| Ingredient (salt) | Amount |
|---|---|
| Mefenamic acid | 250 mg |
| Dicyclomine | 10 mg |
Mefenamic acid
What it is used for
Mainly used for period pain and heavy periods, and for mild to moderate pain.
How it works
An NSAID that lowers prostaglandins in the womb lining, which is why it is used for period pain and heavy periods.
How to take it
Usually 250 to 500 mg three times a day with or after food, for no more than 7 days. For periods, start on the first day of bleeding or when pain begins.
Common side effects
- Stomach pain
- Nausea
- Diarrhoea
- Heartburn
- Drowsiness
- Dizziness
Get medical help straight away if
- Diarrhoea that does not stop (stop taking it)
- Black stools
- Skin rash
- Wheezing
- Swelling of the face
Be careful
Take after food. Can upset the stomach; stop if diarrhoea or rash develops.
Other medicines and interactions
Avoid with other NSAIDs. Raises bleeding risk with warfarin and other blood thinners; can affect kidney function with diuretics and blood pressure medicines.
Pregnancy and breastfeeding
Not advised in pregnancy, especially the last three months. Usually avoided while breastfeeding; ask a doctor about alternatives.
Dicyclomine
What it is used for
Relieves stomach cramps, colic and period cramps.
How it works
An antispasmodic that relaxes the muscle of the gut and relieves cramping pain, for example in IBS and period cramps.
How to take it
Adults usually take 10 to 20 mg three or four times a day before meals. Not for babies under 6 months.
Common side effects
- Dry mouth
- Blurred vision
- Dizziness
- Constipation
- Drowsiness
Get medical help straight away if
- Difficulty passing urine
- Fast heartbeat
- Confusion
- Eye pain (glaucoma)
Be careful
Can cause dry mouth, blurred vision or drowsiness.
Other medicines and interactions
Adds to side effects of other anticholinergic medicines (older antihistamines, tricyclics). Antacids reduce its absorption.
Pregnancy and breastfeeding
Ask a doctor before using in pregnancy; avoid while breastfeeding.
Same composition, other brands (9)
Ask your doctor or pharmacist before switching brands.
Common questions
What is Spasmofirst?
Spasmofirst is a tablet by Wockhardt containing Mefenamic acid 250 mg + Dicyclomine 10 mg.
What is Spasmofirst used for?
Mainly used for period pain and heavy periods, and for mild to moderate pain. Relieves stomach cramps, colic and period cramps.
How should I take Spasmofirst?
Usually 250 to 500 mg three times a day with or after food, for no more than 7 days. For periods, start on the first day of bleeding or when pain begins. Adults usually take 10 to 20 mg three or four times a day before meals. Not for babies under 6 months. Always follow the dose your doctor or the pack gives.
What are the side effects of Spasmofirst?
Common side effects include: Stomach pain, nausea, diarrhoea, heartburn, drowsiness, dizziness, Dry mouth, blurred vision, dizziness, constipation, drowsiness. Get medical help straight away for: Diarrhoea that does not stop (stop taking it), black stools, skin rash, wheezing, swelling of the face, Difficulty passing urine, fast heartbeat, confusion, eye pain (glaucoma).
Does Spasmofirst need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Spasmofirst in pregnancy or while breastfeeding?
Not advised in pregnancy, especially the last three months. Usually avoided while breastfeeding; ask a doctor about alternatives. Ask a doctor before using in pregnancy; avoid while breastfeeding.
What are the substitutes for Spasmofirst?
Brands with the same composition: Meftal-Spas, Mefran Spas, Mefacid Spas, Spasmonil Plus, Mef Spas, Cyclopam-MF, Almefkem Spas, Mefkind-Spas, Biospas Plus. Ask your doctor or pharmacist before switching.
Sources and further reading
- Mefenamic acid: NHS · MedlinePlus
- Dicyclomine: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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