Trajenta Duo 2.5/1000
Trajenta Duo 2.5/1000 is a tablet made by Boehringer Ingelheim that contains Linagliptin 2.5 mg + Metformin 1000 mg. It combines Linagliptin: diabetes medicine (dpp-4 inhibitor) and Metformin: diabetes medicine (biguanide).
| Ingredient (salt) | Amount |
|---|---|
| Linagliptin | 2.5 mg |
| Metformin | 1000 mg |
Linagliptin
What it is used for
Helps the body release insulin after meals to lower blood sugar.
How it works
A DPP-4 inhibitor (gliptin) that does not need a dose change in kidney disease.
How to take it
Usually 5 mg once a day, with or without food.
Common side effects
- Headache
- Stuffy nose or sore throat
- Joint pain
Get medical help straight away if
- Severe stomach pain spreading to the back (pancreatitis)
- Blistering skin (bullous pemphigoid)
- Allergic swelling
Be careful
Report severe stomach pain (rarely pancreatitis).
Other medicines and interactions
Low blood sugar is more likely when combined with sulfonylureas or insulin.
Pregnancy and breastfeeding
Not recommended in pregnancy or while breastfeeding; insulin is preferred.
Metformin
What it is used for
Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.
How it works
The usual first medicine for type 2 diabetes. It lowers the amount of sugar the liver releases and helps the body respond to insulin. On its own it rarely causes low blood sugar and does not cause weight gain.
How to take it
Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop.
Common side effects
- Diarrhoea
- Nausea
- Stomach pain
- Metallic taste
- Reduced appetite
Get medical help straight away if
- Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis)
- Tingling feet or tiredness after years of use (low vitamin B12)
Be careful
Take with food; can cause stomach upset. Stop before scans with contrast or surgery if told.
Other medicines and interactions
Doctors pause it before scans with iodine contrast and before major surgery, and during dehydrating illness (vomiting, diarrhoea). Heavy alcohol raises lactic acidosis risk.
Pregnancy and breastfeeding
Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.
Same ingredients, different strength or form
Common questions
What is Trajenta Duo 2.5/1000?
Trajenta Duo 2.5/1000 is a tablet by Boehringer Ingelheim containing Linagliptin 2.5 mg + Metformin 1000 mg.
What is Trajenta Duo 2.5/1000 used for?
Helps the body release insulin after meals to lower blood sugar. Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.
How should I take Trajenta Duo 2.5/1000?
Usually 5 mg once a day, with or without food. Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop. Always follow the dose your doctor or the pack gives.
What are the side effects of Trajenta Duo 2.5/1000?
Common side effects include: Headache, stuffy nose or sore throat, joint pain, Diarrhoea, nausea, stomach pain, metallic taste, reduced appetite. Get medical help straight away for: Severe stomach pain spreading to the back (pancreatitis), blistering skin (bullous pemphigoid), allergic swelling, Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis), tingling feet or tiredness after years of use (low vitamin B12).
Does Trajenta Duo 2.5/1000 need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Trajenta Duo 2.5/1000 in pregnancy or while breastfeeding?
Not recommended in pregnancy or while breastfeeding; insulin is preferred. Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.
What are the substitutes for Trajenta Duo 2.5/1000?
We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.
Sources and further reading
- Linagliptin: NHS · MedlinePlus
- Metformin: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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