Zita-Met 20/500

Tablet · Glenmark
PRESCRIPTION MEDICINE

Zita-Met 20/500 is a tablet made by Glenmark that contains Teneligliptin 20 mg + Metformin 500 mg. It combines Teneligliptin: diabetes medicine (dpp-4 inhibitor) and Metformin: diabetes medicine (biguanide).

Ingredient (salt)Amount
Teneligliptin20 mg
Metformin500 mg

Teneligliptin

Diabetes medicine (DPP-4 inhibitor)

What it is used for

Helps the body release insulin after meals to lower blood sugar.

How it works

A DPP-4 inhibitor (gliptin) widely used in India; it works like sitagliptin and is cheaper.

How to take it

Usually 20 mg once a day, with or without food.

Common side effects

  • Headache
  • Stuffy nose or sore throat
  • Joint pain

Get medical help straight away if

  • Severe stomach pain spreading to the back (pancreatitis)
  • Blistering skin (bullous pemphigoid)
  • Allergic swelling
  • Palpitations

Be careful

Caution with heart rhythm problems.

Other medicines and interactions

Low blood sugar is more likely when combined with sulfonylureas or insulin.

Pregnancy and breastfeeding

Not recommended in pregnancy or while breastfeeding; insulin is preferred.

Metformin

Diabetes medicine (biguanide)

What it is used for

Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.

How it works

The usual first medicine for type 2 diabetes. It lowers the amount of sugar the liver releases and helps the body respond to insulin. On its own it rarely causes low blood sugar and does not cause weight gain.

How to take it

Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop.

Common side effects

  • Diarrhoea
  • Nausea
  • Stomach pain
  • Metallic taste
  • Reduced appetite

Get medical help straight away if

  • Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis)
  • Tingling feet or tiredness after years of use (low vitamin B12)

Be careful

Take with food; can cause stomach upset. Stop before scans with contrast or surgery if told.

Other medicines and interactions

Doctors pause it before scans with iodine contrast and before major surgery, and during dehydrating illness (vomiting, diarrhoea). Heavy alcohol raises lactic acidosis risk.

Pregnancy and breastfeeding

Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.

Same ingredients, different strength or form

Tenelichoice-M 1000Tenlimac M 1000Dynaglipt-M ForteTenepride M 1000Tenglyn M 1000Tendia M ForteT Glip-M 1000Inogla-M 1000Ziten-M 1000/20Zita Met Plus 20/1000Afoglip M 1000Olymprix M 1000Tenebite M 20/1000

Common questions

What is Zita-Met 20/500?

Zita-Met 20/500 is a tablet by Glenmark containing Teneligliptin 20 mg + Metformin 500 mg.

What is Zita-Met 20/500 used for?

Helps the body release insulin after meals to lower blood sugar. Lowers blood sugar in type 2 diabetes, mainly by reducing sugar made by the liver.

How should I take Zita-Met 20/500?

Usually 20 mg once a day, with or without food. Take with or just after meals to reduce stomach upset; start low (500 mg) and increase slowly. Slow-release tablets are gentler. Keep taking it unless your doctor says to stop. Always follow the dose your doctor or the pack gives.

What are the side effects of Zita-Met 20/500?

Common side effects include: Headache, stuffy nose or sore throat, joint pain, Diarrhoea, nausea, stomach pain, metallic taste, reduced appetite. Get medical help straight away for: Severe stomach pain spreading to the back (pancreatitis), blistering skin (bullous pemphigoid), allergic swelling, palpitations, Severe vomiting, fast breathing, muscle pain and unusual drowsiness (rare lactic acidosis), tingling feet or tiredness after years of use (low vitamin B12).

Does Zita-Met 20/500 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Zita-Met 20/500 in pregnancy or while breastfeeding?

Not recommended in pregnancy or while breastfeeding; insulin is preferred. Sometimes continued in pregnancy under specialist care; insulin is often used. Considered acceptable while breastfeeding.

What are the substitutes for Zita-Met 20/500?

We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.