Alendronate

Bone-strengthening medicine
PRESCRIPTION ONLY IN INDIA

Alendronate is a bone-strengthening medicine found in 1 medicine sold in India, such as Osteofos 70. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

Also called: alendronic acid

What it is used for

Treats and prevents osteoporosis (weak bones).

How it works

A bisphosphonate that slows bone loss and lowers fracture risk in osteoporosis.

How to take it

Weekly 70 mg tablet first thing in the morning with a full glass of plain water, at least 30 minutes before food, drink or other medicines; stay upright for 30 minutes.

Common side effects

  • Heartburn
  • Stomach pain
  • Muscle and bone aches

Get medical help straight away if

  • Pain on swallowing
  • New thigh or groin pain (rare fracture)
  • Jaw pain or slow healing after dental work

Be careful

Usually ONCE A WEEK: take with a full glass of water on an empty stomach and stay upright for 30 minutes.

Other medicines and interactions

Calcium, iron, antacids and food stop it being absorbed. Have dental work done before starting if possible.

Pregnancy and breastfeeding

Not used in pregnancy or while breastfeeding.

Brands of Alendronate (1)

Osteofos 70

Common questions

What is Alendronate used for?

Treats and prevents osteoporosis (weak bones).

How does Alendronate work?

A bisphosphonate that slows bone loss and lowers fracture risk in osteoporosis.

How should I take Alendronate?

Weekly 70 mg tablet first thing in the morning with a full glass of plain water, at least 30 minutes before food, drink or other medicines; stay upright for 30 minutes.

What are the side effects of Alendronate?

Common: Heartburn, stomach pain, muscle and bone aches. Get help straight away for: Pain on swallowing, new thigh or groin pain (rare fracture), jaw pain or slow healing after dental work.

Does Alendronate interact with other medicines?

Calcium, iron, antacids and food stop it being absorbed. Have dental work done before starting if possible.

Is Alendronate safe in pregnancy and breastfeeding?

Not used in pregnancy or while breastfeeding.

Does Alendronate need a prescription in India?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Which brands contain Alendronate?

Osteofos 70.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.