Codeine
Codeine is a opioid painkiller and cough suppressant. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.
Also called: codeine phosphate
What it is used for
Relieves moderate pain (often combined with paracetamol or ibuprofen) and suppresses dry cough.
How it works
An opioid that the liver turns into morphine; used for mild to moderate pain and dry cough. Some people convert too much (risky) or too little.
How to take it
Usually 15 to 60 mg every 4 to 6 hours, maximum 240 mg a day, for no more than 3 days without review.
Common side effects
- Constipation
- Drowsiness
- Nausea
- Dizziness
Get medical help straight away if
- Slow breathing, extreme sleepiness, pinpoint pupils
- Confusion
Be careful
Can cause drowsiness, constipation and dependence; not for children under 12. Avoid alcohol.
Other medicines and interactions
Very dangerous with alcohol, benzodiazepines and other sedatives. Can be habit-forming. Not for children under 12.
Pregnancy and breastfeeding
Avoid in pregnancy, especially near birth. Not recommended while breastfeeding (some mothers produce high morphine levels in milk).
Common questions
What is Codeine used for?
Relieves moderate pain (often combined with paracetamol or ibuprofen) and suppresses dry cough.
How does Codeine work?
An opioid that the liver turns into morphine; used for mild to moderate pain and dry cough. Some people convert too much (risky) or too little.
How should I take Codeine?
Usually 15 to 60 mg every 4 to 6 hours, maximum 240 mg a day, for no more than 3 days without review.
What are the side effects of Codeine?
Common: Constipation, drowsiness, nausea, dizziness. Get help straight away for: Slow breathing, extreme sleepiness, pinpoint pupils, confusion.
Does Codeine interact with other medicines?
Very dangerous with alcohol, benzodiazepines and other sedatives. Can be habit-forming. Not for children under 12.
Is Codeine safe in pregnancy and breastfeeding?
Avoid in pregnancy, especially near birth. Not recommended while breastfeeding (some mothers produce high morphine levels in milk).
Does Codeine need a prescription in India?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Sources and further reading
- Codeine: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.
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