Letrozole

Aromatase inhibitor
PRESCRIPTION ONLY IN INDIA

Letrozole is a aromatase inhibitor found in 1 medicine sold in India, such as Letroz 2.5. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

What it is used for

Treats hormone-sensitive breast cancer; also used to help ovulation in fertility treatment.

How it works

An aromatase inhibitor that lowers oestrogen; used for breast cancer and, off-label, to trigger ovulation in fertility treatment (especially PCOS).

How to take it

Breast cancer: 2.5 mg daily for years. Fertility: usually 2.5 to 7.5 mg daily for 5 days early in the cycle, as directed.

Common side effects

  • Hot flushes
  • Joint pain
  • Tiredness
  • Headache

Get medical help straight away if

  • Bone pain or fracture with long use
  • Low mood

Be careful

Use only under specialist care; can cause joint pain and hot flushes.

Other medicines and interactions

Oestrogen-containing medicines cancel its effect.

Pregnancy and breastfeeding

Must not be taken once pregnant; not for use while breastfeeding.

Brands of Letrozole (1)

Letroz 2.5

Common questions

What is Letrozole used for?

Treats hormone-sensitive breast cancer; also used to help ovulation in fertility treatment.

How does Letrozole work?

An aromatase inhibitor that lowers oestrogen; used for breast cancer and, off-label, to trigger ovulation in fertility treatment (especially PCOS).

How should I take Letrozole?

Breast cancer: 2.5 mg daily for years. Fertility: usually 2.5 to 7.5 mg daily for 5 days early in the cycle, as directed.

What are the side effects of Letrozole?

Common: Hot flushes, joint pain, tiredness, headache. Get help straight away for: Bone pain or fracture with long use, low mood.

Does Letrozole interact with other medicines?

Oestrogen-containing medicines cancel its effect.

Is Letrozole safe in pregnancy and breastfeeding?

Must not be taken once pregnant; not for use while breastfeeding.

Does Letrozole need a prescription in India?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Which brands contain Letrozole?

Letroz 2.5.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.