Loperamide
Loperamide is a anti-diarrhoea found in 2 medicines sold in India, such as Imodium, Eldoper. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.
What it is used for
Slows down loose motions.
How it works
It slows the movement of the gut so more water is absorbed, making stools firmer and less frequent. It acts in the gut and does not reach the brain at normal doses.
How to take it
Adults: 4 mg at first, then 2 mg after each loose stool, maximum 16 mg a day. Drink plenty of fluids or ORS. Not for children under 12 unless a doctor advises.
Common side effects
- Constipation
- Stomach cramps
- Wind
- Dizziness
Get medical help straight away if
- Blood in the stool or high fever (do not use
- See a doctor)
- Swollen tummy
- Diarrhoea lasting more than 2 days
- Fainting or palpitations (very high doses)
Be careful
Do not use with blood in stools or high fever; replace fluids with ORS.
Other medicines and interactions
Ritonavir, itraconazole, ketoconazole and quinidine can raise its level. Do not exceed the dose.
Pregnancy and breastfeeding
Short use is considered acceptable in pregnancy and breastfeeding if needed, but ORS comes first.
Brands of Loperamide (2)
Common questions
What is Loperamide used for?
Slows down loose motions.
How does Loperamide work?
It slows the movement of the gut so more water is absorbed, making stools firmer and less frequent. It acts in the gut and does not reach the brain at normal doses.
How should I take Loperamide?
Adults: 4 mg at first, then 2 mg after each loose stool, maximum 16 mg a day. Drink plenty of fluids or ORS. Not for children under 12 unless a doctor advises.
What are the side effects of Loperamide?
Common: Constipation, stomach cramps, wind, dizziness. Get help straight away for: Blood in the stool or high fever (do not use, see a doctor), swollen tummy, diarrhoea lasting more than 2 days, fainting or palpitations (very high doses).
Does Loperamide interact with other medicines?
Ritonavir, itraconazole, ketoconazole and quinidine can raise its level. Do not exceed the dose.
Is Loperamide safe in pregnancy and breastfeeding?
Short use is considered acceptable in pregnancy and breastfeeding if needed, but ORS comes first.
Does Loperamide need a prescription in India?
It is usually sold without a prescription in India, but ask a pharmacist if you take other medicines or have a long-term illness.
Which brands contain Loperamide?
Eldoper, Imodium.
Sources and further reading
- Loperamide: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.
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