Mebeverine

Antispasmodic
PRESCRIPTION ONLY IN INDIA

Mebeverine is a antispasmodic found in 1 medicine sold in India, such as Colospa 135. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

What it is used for

Relieves cramps and bloating in irritable bowel syndrome.

How it works

An antispasmodic that relaxes gut muscle and eases IBS cramps and bloating, without anticholinergic side effects.

How to take it

Usually 135 mg three times a day 20 minutes before meals, or 200 mg slow-release twice a day.

Common side effects

  • Indigestion
  • Dizziness
  • Rash (rare)

Get medical help straight away if

Allergic reaction

Be careful

Generally well tolerated.

Other medicines and interactions

No important interactions.

Pregnancy and breastfeeding

Ask a doctor before use in pregnancy; acceptable while breastfeeding in most cases.

Brands of Mebeverine (1)

Colospa 135

Common questions

What is Mebeverine used for?

Relieves cramps and bloating in irritable bowel syndrome.

How does Mebeverine work?

An antispasmodic that relaxes gut muscle and eases IBS cramps and bloating, without anticholinergic side effects.

How should I take Mebeverine?

Usually 135 mg three times a day 20 minutes before meals, or 200 mg slow-release twice a day.

What are the side effects of Mebeverine?

Common: Indigestion, dizziness, rash (rare). Get help straight away for: Allergic reaction.

Does Mebeverine interact with other medicines?

No important interactions.

Is Mebeverine safe in pregnancy and breastfeeding?

Ask a doctor before use in pregnancy; acceptable while breastfeeding in most cases.

Does Mebeverine need a prescription in India?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Which brands contain Mebeverine?

Colospa 135.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.