Piperacillin

Antibiotic injection (penicillin)
PRESCRIPTION ONLY IN INDIA

Piperacillin is a antibiotic injection (penicillin) found in 1 medicine sold in India, such as Pipzo 4.5 g. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

What it is used for

Treats serious hospital infections; given by drip.

How it works

A broad-spectrum penicillin injection, combined with tazobactam, for serious hospital infections.

How to take it

Given into a vein or muscle by a health professional, usually in hospital.

Common side effects

  • Diarrhoea
  • Rash
  • Nausea

Get medical help straight away if

  • Allergic reaction (penicillin allergy)
  • Severe diarrhoea
  • Bleeding

Be careful

Not if allergic to penicillin.

Other medicines and interactions

Do not use with a penicillin allergy. Raises methotrexate levels; kidney risk with vancomycin.

Pregnancy and breastfeeding

Used in pregnancy and breastfeeding when needed.

Combination medicines that contain Piperacillin (1)

Pipzo 4.5 g

Common questions

What is Piperacillin used for?

Treats serious hospital infections; given by drip.

How does Piperacillin work?

A broad-spectrum penicillin injection, combined with tazobactam, for serious hospital infections.

How should I take Piperacillin?

Given into a vein or muscle by a health professional, usually in hospital.

What are the side effects of Piperacillin?

Common: Diarrhoea, rash, nausea. Get help straight away for: Allergic reaction (penicillin allergy), severe diarrhoea, bleeding.

Does Piperacillin interact with other medicines?

Do not use with a penicillin allergy. Raises methotrexate levels; kidney risk with vancomycin.

Is Piperacillin safe in pregnancy and breastfeeding?

Used in pregnancy and breastfeeding when needed.

Does Piperacillin need a prescription in India?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Which brands contain Piperacillin?

Pipzo 4.5 g.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.