Saccharomyces boulardii

Probiotic yeast
ALSO SOLD WITHOUT PRESCRIPTION

Saccharomyces boulardii is a probiotic yeast found in 1 medicine sold in India, such as Econorm. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

Also called: saccharomyces

What it is used for

Helps prevent and treat diarrhoea, including antibiotic-related diarrhoea.

How it works

A probiotic yeast that survives antibiotics and may reduce antibiotic-related and infectious diarrhoea.

How to take it

Usually 250 to 500 mg once or twice a day. Can be taken with antibiotics (antifungals kill it).

Common side effects

  • Bloating
  • Thirst
  • Constipation

Get medical help straight away if

Fever or feeling unwell if you have a central line or weak immunity (rare yeast infection of the blood)

Be careful

Avoid in people with very weak immunity or central lines.

Other medicines and interactions

Antifungal medicines such as fluconazole reduce its effect.

Pregnancy and breastfeeding

Generally considered safe; ask a doctor if pregnant.

Brands of Saccharomyces boulardii (1)

Common questions

What is Saccharomyces boulardii used for?

Helps prevent and treat diarrhoea, including antibiotic-related diarrhoea.

How does Saccharomyces boulardii work?

A probiotic yeast that survives antibiotics and may reduce antibiotic-related and infectious diarrhoea.

How should I take Saccharomyces boulardii?

Usually 250 to 500 mg once or twice a day. Can be taken with antibiotics (antifungals kill it).

What are the side effects of Saccharomyces boulardii?

Common: Bloating, thirst, constipation. Get help straight away for: Fever or feeling unwell if you have a central line or weak immunity (rare yeast infection of the blood).

Does Saccharomyces boulardii interact with other medicines?

Antifungal medicines such as fluconazole reduce its effect.

Is Saccharomyces boulardii safe in pregnancy and breastfeeding?

Generally considered safe; ask a doctor if pregnant.

Does Saccharomyces boulardii need a prescription in India?

It is usually sold without a prescription in India, but ask a pharmacist if you take other medicines or have a long-term illness.

Which brands contain Saccharomyces boulardii?

Econorm.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.