Thiocolchicoside

Muscle relaxant
PRESCRIPTION ONLY IN INDIA

Thiocolchicoside is a muscle relaxant found in 2 medicines sold in India, such as Myoril, Zerodol-TH. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

What it is used for

Relaxes muscle spasm, for example in back pain and neck sprain.

How it works

A muscle relaxant derived from the plant colchicum. It relaxes painful muscle spasm by acting on GABA receptors.

How to take it

Tablets: usually 4 to 8 mg twice a day for up to 7 days. Injections: up to 5 days. Do not exceed the prescribed dose or length.

Common side effects

  • Drowsiness
  • Diarrhoea
  • Stomach pain
  • Nausea

Get medical help straight away if

  • Fits (seizures)
  • Allergic swelling
  • Persistent diarrhoea

Be careful

Use only for a few days; not in pregnancy or breastfeeding.

Other medicines and interactions

Drowsiness is worse with alcohol and other sedatives.

Pregnancy and breastfeeding

Must not be used in pregnancy, while breastfeeding, or by women who could become pregnant and are not using contraception, because it may damage chromosomes.

Brands of Thiocolchicoside (1)

Myoril

Combination medicines that contain Thiocolchicoside (1)

Zerodol-TH

Common questions

What is Thiocolchicoside used for?

Relaxes muscle spasm, for example in back pain and neck sprain.

How does Thiocolchicoside work?

A muscle relaxant derived from the plant colchicum. It relaxes painful muscle spasm by acting on GABA receptors.

How should I take Thiocolchicoside?

Tablets: usually 4 to 8 mg twice a day for up to 7 days. Injections: up to 5 days. Do not exceed the prescribed dose or length.

What are the side effects of Thiocolchicoside?

Common: Drowsiness, diarrhoea, stomach pain, nausea. Get help straight away for: Fits (seizures), allergic swelling, persistent diarrhoea.

Does Thiocolchicoside interact with other medicines?

Drowsiness is worse with alcohol and other sedatives.

Is Thiocolchicoside safe in pregnancy and breastfeeding?

Must not be used in pregnancy, while breastfeeding, or by women who could become pregnant and are not using contraception, because it may damage chromosomes.

Does Thiocolchicoside need a prescription in India?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Which brands contain Thiocolchicoside?

Myoril, Zerodol-TH.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.