Vitamin B6 (pyridoxine)
Vitamin B6 is a vitamin found in 1 medicine sold in India, such as Shelcal XT. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.
Also called: pyridoxine, pyridoxal phosphate, pyridoxal 5 phosphate
What it is used for
Supports nerves and blood; given with TB medicines and for some nausea in pregnancy.
How it works
Pyridoxine, needed for nerves and making neurotransmitters; given with isoniazid and sometimes for pregnancy nausea.
How to take it
Usually 10 to 50 mg a day; do not exceed 100 mg a day long term.
Common side effects
- Nausea
- Headache
Get medical help straight away if
Numbness or tingling in hands and feet (nerve damage with high doses over months)
Be careful
Long-term high doses can damage nerves (tingling, numbness).
Other medicines and interactions
High doses reduce the effect of levodopa (without carbidopa) and phenytoin.
Pregnancy and breastfeeding
Low doses are used for pregnancy nausea on medical advice; safe while breastfeeding at usual doses.
Combination medicines that contain Vitamin B6 (1)
Common questions
What is Vitamin B6 used for?
Supports nerves and blood; given with TB medicines and for some nausea in pregnancy.
How does Vitamin B6 work?
Pyridoxine, needed for nerves and making neurotransmitters; given with isoniazid and sometimes for pregnancy nausea.
How should I take Vitamin B6?
Usually 10 to 50 mg a day; do not exceed 100 mg a day long term.
What are the side effects of Vitamin B6?
Common: Nausea, headache. Get help straight away for: Numbness or tingling in hands and feet (nerve damage with high doses over months).
Does Vitamin B6 interact with other medicines?
High doses reduce the effect of levodopa (without carbidopa) and phenytoin.
Is Vitamin B6 safe in pregnancy and breastfeeding?
Low doses are used for pregnancy nausea on medical advice; safe while breastfeeding at usual doses.
Does Vitamin B6 need a prescription in India?
It is usually sold without a prescription in India, but ask a pharmacist if you take other medicines or have a long-term illness.
Which brands contain Vitamin B6?
Shelcal XT.
Sources and further reading
- Vitamin B6 (pyridoxine): NIH Office of Dietary Supplements · NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.
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