Herbs

Goldenseal

Also called: hydrastis

A root containing berberine.

Why people take it
Colds, digestion.
What the evidence says
No good evidence for colds.
How it is usually taken
Usually 500 mg to 1 g of root up to three times a day for short periods.
Be careful
Interacts with many medicines by blocking liver enzymes.
Medicines it can interact with
Blocks breakdown of many medicines (raising their levels), including metformin and some heart medicines.

Other herbs

EchinaceaElderberryGarlic extractGingerPeppermint oilMilk thistleSaw palmettoSt John's wortValerianChamomileLemon balmPassionflowerKavaRhodiolaGinkgoMoringaFenugreekCinnamonBlack seedLicorice

Common questions

What is Goldenseal?

A root containing berberine.

Why do people take Goldenseal?

Colds, digestion.

Does Goldenseal work?

No good evidence for colds.

How much Goldenseal do people take?

Usually 500 mg to 1 g of root up to three times a day for short periods.

Is Goldenseal safe?

Interacts with many medicines by blocking liver enzymes.

Does Goldenseal interact with medicines?

Blocks breakdown of many medicines (raising their levels), including metformin and some heart medicines.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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