Herbs

Grape seed extract

Also called: OPC, proanthocyanidins

Extract of grape seeds, rich in antioxidants.

Why people take it
Blood pressure, circulation.
What the evidence says
Small blood pressure effects.
How it is usually taken
Usually 100 to 300 mg a day.
Be careful
May add to blood thinners.
Medicines it can interact with
May add to blood thinners.

Other herbs

Common questions

What is Grape seed extract?

Extract of grape seeds, rich in antioxidants.

Why do people take Grape seed extract?

Blood pressure, circulation.

Does Grape seed extract work?

Small blood pressure effects.

How much Grape seed extract do people take?

Usually 100 to 300 mg a day.

Is Grape seed extract safe?

May add to blood thinners.

Does Grape seed extract interact with medicines?

May add to blood thinners.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. Supplements are not medicines: they are not tested and approved like drugs before they are sold, and they can interact with medicines. Talk to your doctor or pharmacist before you start one, especially if you are pregnant or breastfeeding, take regular medicines, or have kidney, liver or heart disease.