Esofine 40

Tablet · Macleods Pharma
PRESCRIPTION MEDICINE

Esofine 40 is a tablet made by Macleods Pharma that contains Esomeprazole 40 mg. Esomeprazole is a acid reducer (proton pump inhibitor): reduces stomach acid to treat reflux and ulcers.

Ingredient (salt)Amount
Esomeprazole40 mg

What it is used for

Reduces stomach acid to treat reflux and ulcers.

How it works

A proton pump inhibitor (PPI), the purified active form of omeprazole, used for reflux, ulcers and with antibiotics to clear H. pylori.

How to take it

Take once a day, 30 to 60 minutes before breakfast, swallowed whole (do not crush or chew). Short courses of 2 to 8 weeks are usual; long-term use should be reviewed by a doctor.

Common side effects

  • Headache
  • Diarrhoea
  • Stomach pain
  • Nausea
  • Wind
  • Constipation

Get medical help straight away if

  • Watery diarrhoea that does not stop (possible C. difficile infection)
  • Difficulty swallowing, weight loss or black stools
  • Muscle cramps or spasms (low magnesium with long use)

Be careful

Take before food. Long-term use should be reviewed by a doctor.

Other medicines and interactions

Like omeprazole, it can reduce the effect of clopidogrel and raise levels of diazepam, phenytoin and warfarin.

Pregnancy and breastfeeding

Generally considered acceptable in pregnancy and breastfeeding when needed; ask your doctor.

Same composition, other brands (14)

Nexpro 40Sompraz 40Esoz 40Nexium 40Neksium 40Esomac 40Raciper 40Nexpro Fast 40Esogress 40Esofag 40Esofence 40Sppi 40LupisozYees 40

Ask your doctor or pharmacist before switching brands.

Same ingredients, different strength or form

Nexpro 20Sompraz 20

Common questions

What is Esofine 40?

Esofine 40 is a tablet by Macleods Pharma containing Esomeprazole 40 mg.

What is Esofine 40 used for?

Reduces stomach acid to treat reflux and ulcers.

How should I take Esofine 40?

Take once a day, 30 to 60 minutes before breakfast, swallowed whole (do not crush or chew). Short courses of 2 to 8 weeks are usual; long-term use should be reviewed by a doctor. Always follow the dose your doctor or the pack gives.

What are the side effects of Esofine 40?

Common side effects include: Headache, diarrhoea, stomach pain, nausea, wind, constipation. Get medical help straight away for: Watery diarrhoea that does not stop (possible C. difficile infection), difficulty swallowing, weight loss or black stools, muscle cramps or spasms (low magnesium with long use).

Does Esofine 40 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Esofine 40 in pregnancy or while breastfeeding?

Generally considered acceptable in pregnancy and breastfeeding when needed; ask your doctor.

What are the substitutes for Esofine 40?

Brands with the same composition: Nexpro 40, Sompraz 40, Esoz 40, Nexium 40, Neksium 40, Esomac 40, Raciper 40, Nexpro Fast 40, Esogress 40, Esofag 40, Esofence 40, Sppi 40. Ask your doctor or pharmacist before switching.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.