Kofirax
Kofirax is a syrup (per 5 ml) made by Hetero Drugs that contains Ambroxol 30 mg + Levosalbutamol 1 mg + Guaifenesin 50 mg. It combines Ambroxol: mucus thinner (mucolytic), Levosalbutamol: bronchodilator and Guaifenesin: expectorant.
| Ingredient (salt) | Amount |
|---|---|
| Ambroxol | 30 mg |
| Levosalbutamol | 1 mg |
| Guaifenesin | 50 mg |
Ambroxol
What it is used for
Loosens thick phlegm so it is easier to cough up.
How it works
It thins thick mucus and helps the airways clear it, so coughing brings it up more easily. It also has a mild numbing effect on a sore throat.
How to take it
Adults usually take 30 mg two or three times a day after food, or as syrup. Drink plenty of water.
Common side effects
- Nausea
- Stomach upset
- Altered taste
- Numb mouth or throat
Get medical help straight away if
- Severe skin reaction (rare)
- Allergic swelling
Be careful
Stop and seek help if a skin rash appears.
Other medicines and interactions
Do not take with cough suppressants such as dextromethorphan or codeine for a wet cough, as mucus can build up.
Pregnancy and breastfeeding
Avoid in the first three months of pregnancy and while breastfeeding unless a doctor advises it.
Levosalbutamol
What it is used for
Opens up the airways to ease wheezing and tight chest.
How it works
The active half of salbutamol. It relaxes airway muscles to relieve wheeze and breathlessness.
How to take it
Inhaler or nebuliser as prescribed, usually when needed for symptoms. Tablets and syrups are less effective and cause more side effects than inhalers.
Common side effects
- Tremor
- Fast heartbeat
- Headache
- Muscle cramps
- Nervousness
Get medical help straight away if
- Breathing gets worse straight after using it
- Chest pain
- You need it more often than usual (asthma is getting worse)
Be careful
Can cause shaking hands or a fast heartbeat.
Other medicines and interactions
Beta blockers such as propranolol can block its effect. High doses with steroids, diuretics or theophylline can lower potassium.
Pregnancy and breastfeeding
Inhaled forms can be used in pregnancy and breastfeeding; controlling asthma is important for the baby.
Guaifenesin
What it is used for
Helps bring up phlegm in a chesty cough.
How it works
An expectorant that is thought to make mucus thinner and more watery, so a chesty cough is more productive.
How to take it
Adults usually take 200 to 400 mg every 4 hours as syrup or tablets. Drink plenty of fluids.
Common side effects
- Nausea
- Vomiting
- Stomach upset
- Dizziness
Get medical help straight away if
- Cough lasts more than 3 weeks, or you cough up blood
- Rash
Be careful
Drink plenty of water; not for children under 6 without advice.
Other medicines and interactions
Often combined with cough suppressants, which work in the opposite direction; avoid such mixes for a wet cough.
Pregnancy and breastfeeding
Avoid in the first three months of pregnancy; ask a pharmacist later in pregnancy or while breastfeeding.
Same composition, other brands (13)
Ask your doctor or pharmacist before switching brands.
Common questions
What is Kofirax?
Kofirax is a syrup (per 5 ml) by Hetero Drugs containing Ambroxol 30 mg + Levosalbutamol 1 mg + Guaifenesin 50 mg.
What is Kofirax used for?
Loosens thick phlegm so it is easier to cough up. Opens up the airways to ease wheezing and tight chest. Helps bring up phlegm in a chesty cough.
How should I take Kofirax?
Adults usually take 30 mg two or three times a day after food, or as syrup. Drink plenty of water. Inhaler or nebuliser as prescribed, usually when needed for symptoms. Tablets and syrups are less effective and cause more side effects than inhalers. Adults usually take 200 to 400 mg every 4 hours as syrup or tablets. Drink plenty of fluids. Always follow the dose your doctor or the pack gives.
What are the side effects of Kofirax?
Common side effects include: Nausea, stomach upset, altered taste, numb mouth or throat, Tremor, fast heartbeat, headache, muscle cramps, nervousness, Nausea, vomiting, stomach upset, dizziness. Get medical help straight away for: Severe skin reaction (rare), allergic swelling, Breathing gets worse straight after using it, chest pain, you need it more often than usual (asthma is getting worse), Cough lasts more than 3 weeks, or you cough up blood, rash.
Does Kofirax need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Kofirax in pregnancy or while breastfeeding?
Avoid in the first three months of pregnancy and while breastfeeding unless a doctor advises it. Inhaled forms can be used in pregnancy and breastfeeding; controlling asthma is important for the baby. Avoid in the first three months of pregnancy; ask a pharmacist later in pregnancy or while breastfeeding.
What are the substitutes for Kofirax?
Brands with the same composition: Ascoril LS, Ambrodil-LX, Kofarest-LS, Chericof-LS, Zerotuss XP, Asthalin AX, Mucaryl LS, Ambrolite Levo, Solvin LS, Indikof LS, Deletus LS, Salbetol LS. Ask your doctor or pharmacist before switching.
Sources and further reading
- Ambroxol: NHS · MedlinePlus
- Levosalbutamol: NHS · MedlinePlus
- Guaifenesin: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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