Naxdom 500
Naxdom 500 is a tablet made by Sun Pharma that contains Naproxen 500 mg + Domperidone 10 mg. It combines Naproxen: anti-inflammatory painkiller (nsaid) and Domperidone: anti-nausea, gut motility.
| Ingredient (salt) | Amount |
|---|---|
| Naproxen | 500 mg |
| Domperidone | 10 mg |
Naproxen
What it is used for
Relieves migraine, period pain, arthritis and other pain.
How it works
A longer-acting NSAID for arthritis, period pain, gout and muscle injuries; lower heart risk than some NSAIDs.
How to take it
Usually 250 to 500 mg twice a day with or after food.
Common side effects
- Indigestion
- Heartburn
- Headache
- Drowsiness
Get medical help straight away if
- Black stools
- Much less urine
- Chest pain or breathlessness
- Severe rash
Be careful
Take after food; risk of stomach bleeding.
Other medicines and interactions
Avoid with other NSAIDs and aspirin; bleeding risk with blood thinners and SSRIs; kidney risk with diuretics and ACE inhibitors.
Pregnancy and breastfeeding
Avoid from 20 weeks of pregnancy and ask before earlier use. Short courses may be acceptable while breastfeeding.
Domperidone
What it is used for
Reduces nausea and vomiting and helps the stomach empty, easing bloating.
How it works
It blocks dopamine in the gut and in the vomiting centre, so food moves through the stomach faster and nausea eases. Often paired with a PPI.
How to take it
Adults usually take 10 mg up to three times a day, 15 to 30 minutes before meals, for no more than 7 days. Maximum 30 mg a day.
Common side effects
- Dry mouth
- Headache
- Stomach cramps
- Breast swelling or milk leakage
Get medical help straight away if
Fast or irregular heartbeat, fainting or palpitations (it can affect heart rhythm)
Be careful
Can affect heart rhythm at high doses; avoid with some heart conditions.
Other medicines and interactions
Do not combine with medicines that raise its level or affect heart rhythm: ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, amiodarone and some antipsychotics.
Pregnancy and breastfeeding
Avoid in pregnancy unless a doctor advises it. Passes into breast milk in small amounts; doctors sometimes prescribe it to boost milk, but only under supervision.
Common questions
What is Naxdom 500?
Naxdom 500 is a tablet by Sun Pharma containing Naproxen 500 mg + Domperidone 10 mg.
What is Naxdom 500 used for?
Relieves migraine, period pain, arthritis and other pain. Reduces nausea and vomiting and helps the stomach empty, easing bloating.
How should I take Naxdom 500?
Usually 250 to 500 mg twice a day with or after food. Adults usually take 10 mg up to three times a day, 15 to 30 minutes before meals, for no more than 7 days. Maximum 30 mg a day. Always follow the dose your doctor or the pack gives.
What are the side effects of Naxdom 500?
Common side effects include: Indigestion, heartburn, headache, drowsiness, Dry mouth, headache, stomach cramps, breast swelling or milk leakage. Get medical help straight away for: Black stools, much less urine, chest pain or breathlessness, severe rash, Fast or irregular heartbeat, fainting or palpitations (it can affect heart rhythm).
Does Naxdom 500 need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Naxdom 500 in pregnancy or while breastfeeding?
Avoid from 20 weeks of pregnancy and ask before earlier use. Short courses may be acceptable while breastfeeding. Avoid in pregnancy unless a doctor advises it. Passes into breast milk in small amounts; doctors sometimes prescribe it to boost milk, but only under supervision.
What are the substitutes for Naxdom 500?
We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.
Sources and further reading
- Naproxen: NHS · MedlinePlus
- Domperidone: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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