Neosporin

Ointment/powder · GSK
USUALLY SOLD WITHOUT PRESCRIPTION

Neosporin is a ointment/powder made by GSK that contains Neomycin + Polymyxin B + Bacitracin. It combines Neomycin: antibiotic (skin), Polymyxin B: antibiotic (skin) and Bacitracin: antibiotic (skin).

Ingredient (salt)Amount
Neomycinsee pack
Polymyxin Bsee pack
Bacitracinsee pack

Neomycin

Antibiotic (skin)

What it is used for

Prevents or treats bacterial infection in minor cuts and wounds.

How it works

An aminoglycoside antibiotic used in skin creams and ear or eye drops for surface bacterial infections.

How to take it

Apply thinly 2 to 3 times a day for no more than 7 to 10 days.

Common side effects

Skin allergy (contact dermatitis) is common

Get medical help straight away if

  • Rash spreads or worsens
  • Hearing changes with ear drops in a perforated eardrum

Be careful

Can cause skin allergy in some people.

Other medicines and interactions

Not for large wounds or broken eardrums. Avoid using for long.

Pregnancy and breastfeeding

Short skin use is generally acceptable; ask a doctor.

Polymyxin B

Antibiotic (skin)

What it is used for

Prevents infection in minor wounds.

How it works

An antibiotic that damages bacterial cell membranes, used in skin ointments and eye or ear drops, usually with other antibiotics.

How to take it

Apply or instil as directed for up to 7 days.

Common side effects

Stinging or itching

Get medical help straight away if

  • Rash or swelling
  • No improvement

Be careful

External use only.

Other medicines and interactions

No important interactions when used on the skin.

Pregnancy and breastfeeding

Surface use is generally acceptable.

Bacitracin

Antibiotic (skin)

What it is used for

Prevents infection in minor wounds.

How it works

An antibiotic ointment for small cuts and scrapes, often combined with neomycin and polymyxin.

How to take it

Apply a thin layer 1 to 3 times a day for up to 7 days.

Common side effects

Redness or itching

Get medical help straight away if

  • Allergic rash
  • Wound becomes more painful or red

Be careful

External use only; can cause skin allergy.

Other medicines and interactions

No important interactions.

Pregnancy and breastfeeding

Surface use is generally acceptable.

Common questions

What is Neosporin?

Neosporin is a ointment/powder by GSK containing Neomycin + Polymyxin B + Bacitracin.

What is Neosporin used for?

Prevents or treats bacterial infection in minor cuts and wounds. Prevents infection in minor wounds. Prevents infection in minor wounds.

How should I take Neosporin?

Apply thinly 2 to 3 times a day for no more than 7 to 10 days. Apply or instil as directed for up to 7 days. Apply a thin layer 1 to 3 times a day for up to 7 days. Always follow the dose your doctor or the pack gives.

What are the side effects of Neosporin?

Common side effects include: Skin allergy (contact dermatitis) is common, Stinging or itching, Redness or itching. Get medical help straight away for: Rash spreads or worsens, hearing changes with ear drops in a perforated eardrum, Rash or swelling, no improvement, Allergic rash, wound becomes more painful or red.

Does Neosporin need a prescription?

It is usually sold without a prescription in India, but ask a pharmacist if you take other medicines or have a long-term illness.

Can I take Neosporin in pregnancy or while breastfeeding?

Short skin use is generally acceptable; ask a doctor. Surface use is generally acceptable. Surface use is generally acceptable.

What are the substitutes for Neosporin?

We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.