Polymyxin B

Antibiotic (skin)
ALSO SOLD WITHOUT PRESCRIPTION

Polymyxin B is a antibiotic (skin) found in 1 medicine sold in India, such as Neosporin. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

What it is used for

Prevents infection in minor wounds.

How it works

An antibiotic that damages bacterial cell membranes, used in skin ointments and eye or ear drops, usually with other antibiotics.

How to take it

Apply or instil as directed for up to 7 days.

Common side effects

Stinging or itching

Get medical help straight away if

  • Rash or swelling
  • No improvement

Be careful

External use only.

Other medicines and interactions

No important interactions when used on the skin.

Pregnancy and breastfeeding

Surface use is generally acceptable.

Combination medicines that contain Polymyxin B (1)

Common questions

What is Polymyxin B used for?

Prevents infection in minor wounds.

How does Polymyxin B work?

An antibiotic that damages bacterial cell membranes, used in skin ointments and eye or ear drops, usually with other antibiotics.

How should I take Polymyxin B?

Apply or instil as directed for up to 7 days.

What are the side effects of Polymyxin B?

Common: Stinging or itching. Get help straight away for: Rash or swelling, no improvement.

Does Polymyxin B interact with other medicines?

No important interactions when used on the skin.

Is Polymyxin B safe in pregnancy and breastfeeding?

Surface use is generally acceptable.

Does Polymyxin B need a prescription in India?

It is usually sold without a prescription in India, but ask a pharmacist if you take other medicines or have a long-term illness.

Which brands contain Polymyxin B?

Neosporin.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.