Omez-D
Omez-D is a capsule made by Dr. Reddy's that contains Omeprazole 20 mg + Domperidone 10 mg. It combines Omeprazole: acid reducer (proton pump inhibitor) and Domperidone: anti-nausea, gut motility.
| Ingredient (salt) | Amount |
|---|---|
| Omeprazole | 20 mg |
| Domperidone | 10 mg |
Omeprazole
What it is used for
Reduces stomach acid to treat acidity, reflux and ulcers.
How it works
The first proton pump inhibitor (PPI). It blocks the stomach's acid pumps, relieving heartburn and healing ulcers.
How to take it
Take once a day, 30 to 60 minutes before breakfast, swallowed whole (do not crush or chew). Short courses of 2 to 8 weeks are usual; long-term use should be reviewed by a doctor.
Common side effects
- Headache
- Diarrhoea
- Stomach pain
- Nausea
- Wind
- Constipation
Get medical help straight away if
- Watery diarrhoea that does not stop (possible C. difficile infection)
- Difficulty swallowing, weight loss or black stools
- Muscle cramps or spasms (low magnesium with long use)
Be careful
Take before food. Long-term use should be reviewed by a doctor.
Other medicines and interactions
Reduces the effect of clopidogrel (pantoprazole is often preferred with it). Can raise levels of diazepam, phenytoin and warfarin, and lower absorption of iron, itraconazole and some HIV medicines.
Pregnancy and breastfeeding
Generally considered acceptable in pregnancy and breastfeeding when needed; ask your doctor.
Domperidone
What it is used for
Reduces nausea and vomiting and helps the stomach empty, easing bloating.
How it works
It blocks dopamine in the gut and in the vomiting centre, so food moves through the stomach faster and nausea eases. Often paired with a PPI.
How to take it
Adults usually take 10 mg up to three times a day, 15 to 30 minutes before meals, for no more than 7 days. Maximum 30 mg a day.
Common side effects
- Dry mouth
- Headache
- Stomach cramps
- Breast swelling or milk leakage
Get medical help straight away if
Fast or irregular heartbeat, fainting or palpitations (it can affect heart rhythm)
Be careful
Can affect heart rhythm at high doses; avoid with some heart conditions.
Other medicines and interactions
Do not combine with medicines that raise its level or affect heart rhythm: ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, amiodarone and some antipsychotics.
Pregnancy and breastfeeding
Avoid in pregnancy unless a doctor advises it. Passes into breast milk in small amounts; doctors sometimes prescribe it to boost milk, but only under supervision.
Common questions
What is Omez-D?
Omez-D is a capsule by Dr. Reddy's containing Omeprazole 20 mg + Domperidone 10 mg.
What is Omez-D used for?
Reduces stomach acid to treat acidity, reflux and ulcers. Reduces nausea and vomiting and helps the stomach empty, easing bloating.
How should I take Omez-D?
Take once a day, 30 to 60 minutes before breakfast, swallowed whole (do not crush or chew). Short courses of 2 to 8 weeks are usual; long-term use should be reviewed by a doctor. Adults usually take 10 mg up to three times a day, 15 to 30 minutes before meals, for no more than 7 days. Maximum 30 mg a day. Always follow the dose your doctor or the pack gives.
What are the side effects of Omez-D?
Common side effects include: Headache, diarrhoea, stomach pain, nausea, wind, constipation, Dry mouth, headache, stomach cramps, breast swelling or milk leakage. Get medical help straight away for: Watery diarrhoea that does not stop (possible C. difficile infection), difficulty swallowing, weight loss or black stools, muscle cramps or spasms (low magnesium with long use), Fast or irregular heartbeat, fainting or palpitations (it can affect heart rhythm).
Does Omez-D need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Omez-D in pregnancy or while breastfeeding?
Generally considered acceptable in pregnancy and breastfeeding when needed; ask your doctor. Avoid in pregnancy unless a doctor advises it. Passes into breast milk in small amounts; doctors sometimes prescribe it to boost milk, but only under supervision.
What are the substitutes for Omez-D?
We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.
Sources and further reading
- Omeprazole: NHS · MedlinePlus
- Domperidone: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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