Synasma 400

Tablet · Cipla
PRESCRIPTION MEDICINE

Synasma 400 is a tablet made by Cipla that contains Doxofylline 400 mg. Doxofylline is a bronchodilator: opens the airways in asthma and COPD.

Ingredient (salt)Amount
Doxofylline400 mg

What it is used for

Opens the airways in asthma and COPD.

How it works

A theophylline-like bronchodilator with fewer heart and stomach side effects, popular in India for asthma and COPD.

How to take it

Usually 400 mg once or twice a day after food.

Common side effects

  • Nausea
  • Headache
  • Trouble sleeping
  • Palpitations

Get medical help straight away if

Very fast heartbeat, vomiting or seizures

Be careful

Can cause nausea or a fast heartbeat.

Other medicines and interactions

Erythromycin, ciprofloxacin and similar medicines can raise its levels. Avoid much caffeine.

Pregnancy and breastfeeding

Not recommended in pregnancy or while breastfeeding unless a doctor advises it.

Common questions

What is Synasma 400?

Synasma 400 is a tablet by Cipla containing Doxofylline 400 mg.

What is Synasma 400 used for?

Opens the airways in asthma and COPD.

How should I take Synasma 400?

Usually 400 mg once or twice a day after food. Always follow the dose your doctor or the pack gives.

What are the side effects of Synasma 400?

Common side effects include: Nausea, headache, trouble sleeping, palpitations. Get medical help straight away for: Very fast heartbeat, vomiting or seizures.

Does Synasma 400 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Synasma 400 in pregnancy or while breastfeeding?

Not recommended in pregnancy or while breastfeeding unless a doctor advises it.

What are the substitutes for Synasma 400?

We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.