Taxim-OF
Taxim-OF is a tablet made by Alkem that contains Cefixime 200 mg + Ofloxacin 200 mg. It combines Cefixime: antibiotic (cephalosporin) and Ofloxacin: antibiotic (fluoroquinolone).
Cefixime
What it is used for
Treats infections such as typhoid, urine infections and throat or chest infections.
How it works
A third-generation oral cephalosporin antibiotic used for typhoid, urinary infections, throat and ear infections and gonorrhoea.
How to take it
Usually 200 mg twice a day or 400 mg once a day, with or without food. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise.
Common side effects
- Diarrhoea
- Stomach pain
- Nausea
- Headache
Get medical help straight away if
- Severe watery diarrhoea
- Rash with blistering
- Swelling of face or breathing trouble
Be careful
Finish the course. Can cause loose motions.
Other medicines and interactions
Tell your doctor if you are allergic to penicillin; a small number of people react to both. May affect warfarin.
Pregnancy and breastfeeding
Considered acceptable in pregnancy and breastfeeding.
Ofloxacin
What it is used for
Treats urine, gut, chest and some ear and eye infections.
How it works
A fluoroquinolone antibiotic, also used as ear and eye drops, often combined with ornidazole for gut infections.
How to take it
Tablets usually 200 to 400 mg twice a day. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise.
Common side effects
- Nausea
- Diarrhoea
- Dizziness
- Trouble sleeping
Get medical help straight away if
- Tendon pain or swelling, especially the heel (stop and rest)
- Tingling, numbness or burning in the hands or feet
- Mood changes or confusion
- Severe diarrhoea
- Palpitations
Be careful
Can rarely damage tendons and nerves; avoid antacids at the same time.
Other medicines and interactions
Antacids, iron, zinc, calcium and milk taken at the same time block absorption; separate by at least 2 hours before or 6 hours after. Raises tendon risk with steroids. Can affect warfarin, diabetes medicines (blood sugar swings) and heart rhythm medicines.
Pregnancy and breastfeeding
Usually avoided in pregnancy and while breastfeeding unless no other antibiotic will work.
Same composition, other brands (1)
Ask your doctor or pharmacist before switching brands.
Common questions
What is Taxim-OF?
Taxim-OF is a tablet by Alkem containing Cefixime 200 mg + Ofloxacin 200 mg.
What is Taxim-OF used for?
Treats infections such as typhoid, urine infections and throat or chest infections. Treats urine, gut, chest and some ear and eye infections.
How should I take Taxim-OF?
Usually 200 mg twice a day or 400 mg once a day, with or without food. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise. Tablets usually 200 to 400 mg twice a day. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise. Always follow the dose your doctor or the pack gives.
What are the side effects of Taxim-OF?
Common side effects include: Diarrhoea, stomach pain, nausea, headache, Nausea, diarrhoea, dizziness, trouble sleeping. Get medical help straight away for: Severe watery diarrhoea, rash with blistering, swelling of face or breathing trouble, Tendon pain or swelling, especially the heel (stop and rest), tingling, numbness or burning in the hands or feet, mood changes or confusion, severe diarrhoea, palpitations.
Does Taxim-OF need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Taxim-OF in pregnancy or while breastfeeding?
Considered acceptable in pregnancy and breastfeeding. Usually avoided in pregnancy and while breastfeeding unless no other antibiotic will work.
What are the substitutes for Taxim-OF?
Brands with the same composition: Topcef-O 200. Ask your doctor or pharmacist before switching.
Sources and further reading
- Cefixime: NHS · MedlinePlus
- Ofloxacin: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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