Topcef-O 200

Tablet · Torrent
PRESCRIPTION MEDICINE

Topcef-O 200 is a tablet made by Torrent that contains Cefixime 200 mg + Ofloxacin 200 mg. It combines Cefixime: antibiotic (cephalosporin) and Ofloxacin: antibiotic (fluoroquinolone).

Ingredient (salt)Amount
Cefixime200 mg
Ofloxacin200 mg

Cefixime

Antibiotic (cephalosporin)

What it is used for

Treats infections such as typhoid, urine infections and throat or chest infections.

How it works

A third-generation oral cephalosporin antibiotic used for typhoid, urinary infections, throat and ear infections and gonorrhoea.

How to take it

Usually 200 mg twice a day or 400 mg once a day, with or without food. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise.

Common side effects

  • Diarrhoea
  • Stomach pain
  • Nausea
  • Headache

Get medical help straight away if

  • Severe watery diarrhoea
  • Rash with blistering
  • Swelling of face or breathing trouble

Be careful

Finish the course. Can cause loose motions.

Other medicines and interactions

Tell your doctor if you are allergic to penicillin; a small number of people react to both. May affect warfarin.

Pregnancy and breastfeeding

Considered acceptable in pregnancy and breastfeeding.

Ofloxacin

Antibiotic (fluoroquinolone)

What it is used for

Treats urine, gut, chest and some ear and eye infections.

How it works

A fluoroquinolone antibiotic, also used as ear and eye drops, often combined with ornidazole for gut infections.

How to take it

Tablets usually 200 to 400 mg twice a day. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise.

Common side effects

  • Nausea
  • Diarrhoea
  • Dizziness
  • Trouble sleeping

Get medical help straight away if

  • Tendon pain or swelling, especially the heel (stop and rest)
  • Tingling, numbness or burning in the hands or feet
  • Mood changes or confusion
  • Severe diarrhoea
  • Palpitations

Be careful

Can rarely damage tendons and nerves; avoid antacids at the same time.

Other medicines and interactions

Antacids, iron, zinc, calcium and milk taken at the same time block absorption; separate by at least 2 hours before or 6 hours after. Raises tendon risk with steroids. Can affect warfarin, diabetes medicines (blood sugar swings) and heart rhythm medicines.

Pregnancy and breastfeeding

Usually avoided in pregnancy and while breastfeeding unless no other antibiotic will work.

Same composition, other brands (1)

Taxim-OF

Ask your doctor or pharmacist before switching brands.

Common questions

What is Topcef-O 200?

Topcef-O 200 is a tablet by Torrent containing Cefixime 200 mg + Ofloxacin 200 mg.

What is Topcef-O 200 used for?

Treats infections such as typhoid, urine infections and throat or chest infections. Treats urine, gut, chest and some ear and eye infections.

How should I take Topcef-O 200?

Usually 200 mg twice a day or 400 mg once a day, with or without food. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise. Tablets usually 200 to 400 mg twice a day. Take at evenly spaced times and finish the full course even when you feel better, unless your doctor says otherwise. Always follow the dose your doctor or the pack gives.

What are the side effects of Topcef-O 200?

Common side effects include: Diarrhoea, stomach pain, nausea, headache, Nausea, diarrhoea, dizziness, trouble sleeping. Get medical help straight away for: Severe watery diarrhoea, rash with blistering, swelling of face or breathing trouble, Tendon pain or swelling, especially the heel (stop and rest), tingling, numbness or burning in the hands or feet, mood changes or confusion, severe diarrhoea, palpitations.

Does Topcef-O 200 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Topcef-O 200 in pregnancy or while breastfeeding?

Considered acceptable in pregnancy and breastfeeding. Usually avoided in pregnancy and while breastfeeding unless no other antibiotic will work.

What are the substitutes for Topcef-O 200?

Brands with the same composition: Taxim-OF. Ask your doctor or pharmacist before switching.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.