Vymada 50
Vymada 50 is a tablet made by Novartis that contains Sacubitril 24 mg + Valsartan 26 mg. It combines Sacubitril: heart failure medicine and Valsartan: blood pressure medicine (arb).
| Ingredient (salt) | Amount |
|---|---|
| Sacubitril | 24 mg |
| Valsartan | 26 mg |
Sacubitril
What it is used for
Combined with valsartan to help a weak heart pump better and reduce hospital stays.
How it works
Blocks neprilysin, boosting the body's own natural salt- and water-removing hormones; always combined with valsartan for heart failure.
How to take it
Usually twice a day, increased gradually. Stop any ACE inhibitor 36 hours before starting.
Common side effects
- Low blood pressure
- Dizziness
- High potassium
- Cough
Get medical help straight away if
- Swelling of the face or throat
- Fainting
- Much less urine
Be careful
Can lower blood pressure; not with ACE inhibitors or in pregnancy.
Other medicines and interactions
Never take with an ACE inhibitor. Potassium supplements and NSAIDs raise risk.
Pregnancy and breastfeeding
Must not be used in pregnancy; not recommended while breastfeeding.
Valsartan
What it is used for
Lowers blood pressure and is used in heart failure.
How it works
An angiotensin receptor blocker (ARB), also combined with sacubitril for heart failure.
How to take it
Usually 80 to 320 mg once a day (or twice for heart failure).
Common side effects
- Dizziness, especially when standing up
- Tiredness
- Raised potassium
Get medical help straight away if
- Swelling of the face, lips or tongue
- Fainting
- Much less urine
- Muscle weakness or irregular heartbeat (high potassium)
Be careful
Not in pregnancy; can raise potassium.
Other medicines and interactions
Potassium supplements, salt substitutes, spironolactone and NSAIDs raise potassium and kidney risk. Do not combine with an ACE inhibitor or aliskiren. Raises lithium levels.
Pregnancy and breastfeeding
Must not be used in pregnancy (it harms the baby's kidneys); switch before trying to conceive. Ask your doctor about breastfeeding; other medicines may be preferred.
Common questions
What is Vymada 50?
Vymada 50 is a tablet by Novartis containing Sacubitril 24 mg + Valsartan 26 mg.
What is Vymada 50 used for?
Combined with valsartan to help a weak heart pump better and reduce hospital stays. Lowers blood pressure and is used in heart failure.
How should I take Vymada 50?
Usually twice a day, increased gradually. Stop any ACE inhibitor 36 hours before starting. Usually 80 to 320 mg once a day (or twice for heart failure). Always follow the dose your doctor or the pack gives.
What are the side effects of Vymada 50?
Common side effects include: Low blood pressure, dizziness, high potassium, cough, Dizziness, especially when standing up, tiredness, raised potassium. Get medical help straight away for: Swelling of the face or throat, fainting, much less urine, Swelling of the face, lips or tongue, fainting, much less urine, muscle weakness or irregular heartbeat (high potassium).
Does Vymada 50 need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Vymada 50 in pregnancy or while breastfeeding?
Must not be used in pregnancy; not recommended while breastfeeding. Must not be used in pregnancy (it harms the baby's kidneys); switch before trying to conceive. Ask your doctor about breastfeeding; other medicines may be preferred.
What are the substitutes for Vymada 50?
We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.
Sources and further reading
- Sacubitril: NHS · MedlinePlus
- Valsartan: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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