Avoid

⛔ Best avoided

SARMs

Also called: ostarine, ligandrol, RAD-140

Unapproved drugs sold as muscle-building "supplements".

Why people take it
Muscle growth.
What the evidence says
Not approved for any use.
How it is usually taken
Not recommended at any amount; see the warning above.
Be careful
Liver damage, heart risks and hormone shutdown; banned in sport.
Medicines it can interact with
Dangerous interactions are reported; do not combine with any medicine.

Other avoid

EphedraBitter orangeDMAAComfrey (by mouth)AristolochiaGermanderChaparralPennyroyalLobeliaKratomProhormonesTianeptinePhenibut

Common questions

What is SARMs?

Unapproved drugs sold as muscle-building "supplements".

Why do people take SARMs?

Muscle growth.

Does SARMs work?

Not approved for any use.

How much SARMs do people take?

Not recommended at any amount; see the warning above.

Is SARMs safe?

Liver damage, heart risks and hormone shutdown; banned in sport.

Does SARMs interact with medicines?

Dangerous interactions are reported; do not combine with any medicine.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. Supplements are not medicines: they are not tested and approved like drugs before they are sold, and they can interact with medicines. Talk to your doctor or pharmacist before you start one, especially if you are pregnant or breastfeeding, take regular medicines, or have kidney, liver or heart disease.