Avoid
⛔ Best avoidedTianeptine
Also called: zaza, tianna
An antidepressant in some countries, sold illegally as a supplement in others.
- Why people take it
- Mood, energy.
- What the evidence says
- Not a supplement.
- How it is usually taken
- Not recommended at any amount; see the warning above.
- Be careful
- Addictive with opioid-like effects; overdoses and deaths reported.
- Medicines it can interact with
- Dangerous with opioids, alcohol and sedatives.
Other avoid
Common questions
What is Tianeptine?
An antidepressant in some countries, sold illegally as a supplement in others.
Why do people take Tianeptine?
Mood, energy.
Does Tianeptine work?
Not a supplement.
How much Tianeptine do people take?
Not recommended at any amount; see the warning above.
Is Tianeptine safe?
Addictive with opioid-like effects; overdoses and deaths reported.
Does Tianeptine interact with medicines?
Dangerous with opioids, alcohol and sedatives.
Sources and further reading
Last reviewed 31 October 2026. Written by Satya Babu.
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