Spherox
What Spherox is used for
Repair of symptomatic articular cartilage defects of the femoral condyle and the patella of the knee (International Cartilage Repair Society [ICRS] grade III or IV) with defect sizes up to 10 cm2 in adults.
Approved use, as published by the European Medicines Agency.
What the labels mean
- Advanced therapy: a gene, cell or tissue-engineered medicine.
Key facts
- Brand
- Spherox
- Active substance
- spheroids of human autologous matrix-associated chondrocytes
- Disease area
- Cartilage Diseases
- Medicine group
- Other drugs for disorders of the musculo-skeletal system
- ATC code
- M09AX02
- Marketing authorisation holder
- CO.DON Gmbh
- Authorised in the EU since
- 2017
Official information
Specialist medicine: started and supervised by a specialist doctor or hospital. This page is a plain-language summary of public official information, not medical advice; follow your doctor and the official product information.
Common questions
What is Spherox used for?
Repair of symptomatic articular cartilage defects of the femoral condyle and the patella of the knee (International Cartilage Repair Society [ICRS] grade III or IV) with defect sizes up to 10 cm2 in adults.
What is the active substance in Spherox?
Spherox contains spheroids of human autologous matrix-associated chondrocytes.
Who makes Spherox?
The EU marketing authorisation holder is CO.DON Gmbh.
Source: European Medicines Agency medicines data (ema.europa.eu), reproduced with acknowledgement of the source. Page made 5 November 2026 by Satya Babu.
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