Alyftrek
Alyftrek ingredients
| Active ingredient | Strength |
|---|---|
| Vanzacaftor | 4 mg/1, 10 mg/1 |
| Tezacaftor | 20 mg/1, 50 mg/1 |
| Deutivacaftor | 50 mg/1, 125 mg/1 |
What Alyftrek is used for
The FDA lists the approved uses on the official label (below). In the EU, ivacaftor;tezacaftor;elexacaftor is approved as Kaftrio for:
Kaftrio tablets are indicated in a combination regimen with ivacaftor for the treatment of cystic fibrosis (CF) in patients aged 6 years and older who have at least one non-Class I mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Kaftrio granules are indicated in a combination regimen with ivacaftor for the treatment of cystic fibrosis (CF) in paediatric patients aged 2 to less than 6 years who have at least one non-Class I mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
EU wording from the European Medicines Agency; US approved uses can differ.
Key facts
- Brand
- Alyftrek
- Generic name
- Vanzacaftor, tezacaftor, and deutivacaftor
- Made by
- Vertex Pharmaceuticals Incorporated
- Forms
- Tablet, Film Coated
- Given
- Oral
- Drug class
- Cystic Fibrosis Transmembrane Conductance Regulator Potentiator
- FDA approval
- New drug application (NDA) NDA218730
- On the US market since
- 2024
Official information
- Alyftrek prescribing information (FDA label) on DailyMed
- MedlinePlus drug information (search for Vanzacaftor, tezacaftor, and deutivacaftor)
Specialist medicine: started and supervised by a specialist doctor or hospital. This page is a plain-language summary of public official information, not medical advice; follow your doctor and the official product information.
Common questions
What is Alyftrek?
Alyftrek (Vanzacaftor, tezacaftor, and deutivacaftor) is a specialist medicine made by Vertex Pharmaceuticals Incorporated, approved by the US FDA.
What are the ingredients of Alyftrek?
Alyftrek contains Vanzacaftor (4 mg/1, 10 mg/1); Tezacaftor (20 mg/1, 50 mg/1); Deutivacaftor (50 mg/1, 125 mg/1).
Is Alyftrek approved in Europe?
The same active substance is approved in the EU as Kaftrio, Alyftrek, Symkevi.
From the FDA National Drug Code directory (open.fda.gov, public domain) and the European Medicines Agency medicines list. Page made 5 November 2026 by Satya Babu.
← All specialty medicines, USA