Zokinvy

Lonafarnib · Sentynl Therapeutics, Inc.
PRESCRIPTION ONLY (USA)

Zokinvy ingredients

Active ingredientStrength
Lonafarnib50 mg/1, 75 mg/1

What Zokinvy is used for

The FDA lists the approved uses on the official label (below). In the EU, lonafarnib is approved as Zokinvy for:

Zokinvy is indicated for the treatment of patients 12 months of age and older with a genetically confirmed diagnosis of Hutchinson-Gilford progeria syndrome or a processing-deficient progeroid laminopathy associated with either a heterozygous LMNA mutation with progerin-like protein accumulation or a homozygous or compound heterozygous ZMPSTE24 mutation.

EU wording from the European Medicines Agency; US approved uses can differ.

Key facts

Brand
Zokinvy
Generic name
Lonafarnib
Made by
Sentynl Therapeutics, Inc.
Forms
Capsule
Given
Oral
Drug class
Farnesyltransferase Inhibitor
FDA approval
New drug application (NDA) NDA213969
On the US market since
2025

Official information

Specialist medicine: started and supervised by a specialist doctor or hospital. This page is a plain-language summary of public official information, not medical advice; follow your doctor and the official product information.

Common questions

What is Zokinvy?

Zokinvy (Lonafarnib) is a specialist medicine made by Sentynl Therapeutics, Inc., approved by the US FDA.

What are the ingredients of Zokinvy?

Zokinvy contains Lonafarnib (50 mg/1, 75 mg/1).

Is Zokinvy approved in Europe?

The same active substance is approved in the EU as Zokinvy.

From the FDA National Drug Code directory (open.fda.gov, public domain) and the European Medicines Agency medicines list. Page made 5 November 2026 by Satya Babu.

← All specialty medicines, USA

For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.