Nexpro RD
Nexpro RD is a capsule made by Torrent that contains Esomeprazole 40 mg + Domperidone 30 mg (slow release). It combines Esomeprazole: acid reducer (proton pump inhibitor) and Domperidone: anti-nausea, gut motility.
| Ingredient (salt) | Amount |
|---|---|
| Esomeprazole | 40 mg |
| Domperidone | 30 mg (slow release) |
Esomeprazole
What it is used for
Reduces stomach acid to treat reflux and ulcers.
How it works
A proton pump inhibitor (PPI), the purified active form of omeprazole, used for reflux, ulcers and with antibiotics to clear H. pylori.
How to take it
Take once a day, 30 to 60 minutes before breakfast, swallowed whole (do not crush or chew). Short courses of 2 to 8 weeks are usual; long-term use should be reviewed by a doctor.
Common side effects
- Headache
- Diarrhoea
- Stomach pain
- Nausea
- Wind
- Constipation
Get medical help straight away if
- Watery diarrhoea that does not stop (possible C. difficile infection)
- Difficulty swallowing, weight loss or black stools
- Muscle cramps or spasms (low magnesium with long use)
Be careful
Take before food. Long-term use should be reviewed by a doctor.
Other medicines and interactions
Like omeprazole, it can reduce the effect of clopidogrel and raise levels of diazepam, phenytoin and warfarin.
Pregnancy and breastfeeding
Generally considered acceptable in pregnancy and breastfeeding when needed; ask your doctor.
Domperidone
What it is used for
Reduces nausea and vomiting and helps the stomach empty, easing bloating.
How it works
It blocks dopamine in the gut and in the vomiting centre, so food moves through the stomach faster and nausea eases. Often paired with a PPI.
How to take it
Adults usually take 10 mg up to three times a day, 15 to 30 minutes before meals, for no more than 7 days. Maximum 30 mg a day.
Common side effects
- Dry mouth
- Headache
- Stomach cramps
- Breast swelling or milk leakage
Get medical help straight away if
Fast or irregular heartbeat, fainting or palpitations (it can affect heart rhythm)
Be careful
Can affect heart rhythm at high doses; avoid with some heart conditions.
Other medicines and interactions
Do not combine with medicines that raise its level or affect heart rhythm: ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, amiodarone and some antipsychotics.
Pregnancy and breastfeeding
Avoid in pregnancy unless a doctor advises it. Passes into breast milk in small amounts; doctors sometimes prescribe it to boost milk, but only under supervision.
Common questions
What is Nexpro RD?
Nexpro RD is a capsule by Torrent containing Esomeprazole 40 mg + Domperidone 30 mg (slow release).
What is Nexpro RD used for?
Reduces stomach acid to treat reflux and ulcers. Reduces nausea and vomiting and helps the stomach empty, easing bloating.
How should I take Nexpro RD?
Take once a day, 30 to 60 minutes before breakfast, swallowed whole (do not crush or chew). Short courses of 2 to 8 weeks are usual; long-term use should be reviewed by a doctor. Adults usually take 10 mg up to three times a day, 15 to 30 minutes before meals, for no more than 7 days. Maximum 30 mg a day. Always follow the dose your doctor or the pack gives.
What are the side effects of Nexpro RD?
Common side effects include: Headache, diarrhoea, stomach pain, nausea, wind, constipation, Dry mouth, headache, stomach cramps, breast swelling or milk leakage. Get medical help straight away for: Watery diarrhoea that does not stop (possible C. difficile infection), difficulty swallowing, weight loss or black stools, muscle cramps or spasms (low magnesium with long use), Fast or irregular heartbeat, fainting or palpitations (it can affect heart rhythm).
Does Nexpro RD need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Nexpro RD in pregnancy or while breastfeeding?
Generally considered acceptable in pregnancy and breastfeeding when needed; ask your doctor. Avoid in pregnancy unless a doctor advises it. Passes into breast milk in small amounts; doctors sometimes prescribe it to boost milk, but only under supervision.
What are the substitutes for Nexpro RD?
We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.
Sources and further reading
- Esomeprazole: NHS · MedlinePlus
- Domperidone: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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