Pentopan DSR

Capsule · Ozone Pharma
PRESCRIPTION MEDICINE

Pentopan DSR is a capsule made by Ozone Pharma that contains Pantoprazole 40 mg + Domperidone 30 mg (slow release). It combines Pantoprazole: acid reducer (proton pump inhibitor) and Domperidone: anti-nausea, gut motility.

Ingredient (salt)Amount
Pantoprazole40 mg
Domperidone30 mg (slow release)

Pantoprazole

Acid reducer (proton pump inhibitor)

What it is used for

Reduces stomach acid to treat acidity, heartburn, reflux and ulcers.

How it works

A proton pump inhibitor (PPI). It switches off the acid pumps in the stomach lining, cutting acid by up to 90 percent, which lets ulcers and an inflamed food pipe heal.

How to take it

Take once a day, 30 to 60 minutes before breakfast, swallowed whole (do not crush or chew). Short courses of 2 to 8 weeks are usual; long-term use should be reviewed by a doctor.

Common side effects

  • Headache
  • Diarrhoea
  • Stomach pain
  • Nausea
  • Wind
  • Constipation

Get medical help straight away if

  • Watery diarrhoea that does not stop (possible C. difficile infection)
  • Difficulty swallowing, weight loss or black stools
  • Muscle cramps or spasms (low magnesium with long use)

Be careful

Take before food. Long-term use should be reviewed by a doctor.

Other medicines and interactions

It lowers absorption of medicines that need acid (itraconazole, ketoconazole, some HIV medicines, iron). Long-term use can lower vitamin B12 and magnesium. Raises methotrexate levels at high doses.

Pregnancy and breastfeeding

Generally considered acceptable in pregnancy and breastfeeding when needed; ask your doctor.

Domperidone

Anti-nausea, gut motility

What it is used for

Reduces nausea and vomiting and helps the stomach empty, easing bloating.

How it works

It blocks dopamine in the gut and in the vomiting centre, so food moves through the stomach faster and nausea eases. Often paired with a PPI.

How to take it

Adults usually take 10 mg up to three times a day, 15 to 30 minutes before meals, for no more than 7 days. Maximum 30 mg a day.

Common side effects

  • Dry mouth
  • Headache
  • Stomach cramps
  • Breast swelling or milk leakage

Get medical help straight away if

Fast or irregular heartbeat, fainting or palpitations (it can affect heart rhythm)

Be careful

Can affect heart rhythm at high doses; avoid with some heart conditions.

Other medicines and interactions

Do not combine with medicines that raise its level or affect heart rhythm: ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, amiodarone and some antipsychotics.

Pregnancy and breastfeeding

Avoid in pregnancy unless a doctor advises it. Passes into breast milk in small amounts; doctors sometimes prescribe it to boost milk, but only under supervision.

Same composition, other brands (10)

Pan-DPantocid DSRPantosec DSRPantakind-DSRNupenta-DSRPansec DSRPantium DSRProtera DUlpan-DSRPantodac DSR

Ask your doctor or pharmacist before switching brands.

Same ingredients, different strength or form

Pantop-D

Common questions

What is Pentopan DSR?

Pentopan DSR is a capsule by Ozone Pharma containing Pantoprazole 40 mg + Domperidone 30 mg (slow release).

What is Pentopan DSR used for?

Reduces stomach acid to treat acidity, heartburn, reflux and ulcers. Reduces nausea and vomiting and helps the stomach empty, easing bloating.

How should I take Pentopan DSR?

Take once a day, 30 to 60 minutes before breakfast, swallowed whole (do not crush or chew). Short courses of 2 to 8 weeks are usual; long-term use should be reviewed by a doctor. Adults usually take 10 mg up to three times a day, 15 to 30 minutes before meals, for no more than 7 days. Maximum 30 mg a day. Always follow the dose your doctor or the pack gives.

What are the side effects of Pentopan DSR?

Common side effects include: Headache, diarrhoea, stomach pain, nausea, wind, constipation, Dry mouth, headache, stomach cramps, breast swelling or milk leakage. Get medical help straight away for: Watery diarrhoea that does not stop (possible C. difficile infection), difficulty swallowing, weight loss or black stools, muscle cramps or spasms (low magnesium with long use), Fast or irregular heartbeat, fainting or palpitations (it can affect heart rhythm).

Does Pentopan DSR need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Pentopan DSR in pregnancy or while breastfeeding?

Generally considered acceptable in pregnancy and breastfeeding when needed; ask your doctor. Avoid in pregnancy unless a doctor advises it. Passes into breast milk in small amounts; doctors sometimes prescribe it to boost milk, but only under supervision.

What are the substitutes for Pentopan DSR?

Brands with the same composition: Pan-D, Pantocid DSR, Pantosec DSR, Pantakind-DSR, Nupenta-DSR, Pansec DSR, Pantium DSR, Protera D, Ulpan-DSR, Pantodac DSR. Ask your doctor or pharmacist before switching.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.