Zyloric 100

Tablet · GSK
PRESCRIPTION MEDICINE

Zyloric 100 is a tablet made by GSK that contains Allopurinol 100 mg. Allopurinol is a gout preventer: lowers uric acid to prevent gout attacks and kidney stones.

Ingredient (salt)Amount
Allopurinol100 mg

What it is used for

Lowers uric acid to prevent gout attacks and kidney stones.

How it works

Reduces uric acid production, preventing gout attacks and some kidney stones.

How to take it

Usually 100 to 300 mg once a day after food, increased slowly; drink plenty of water. Gout flares can rise in the first months; your doctor may add colchicine.

Common side effects

  • Rash
  • Nausea
  • Diarrhoea

Get medical help straight away if

  • Any rash, especially with fever, blisters or mouth sores (stop at once
  • Higher risk in people of Han Chinese, Thai or Korean origin with HLA-B*5801)

Be careful

Do not start during an attack; stop and see a doctor if a rash appears.

Other medicines and interactions

Greatly raises azathioprine and mercaptopurine levels. Raises warfarin effect slightly.

Pregnancy and breastfeeding

Not recommended in pregnancy or while breastfeeding.

Same composition, other brands (1)

Ciploric 100

Ask your doctor or pharmacist before switching brands.

Same ingredients, different strength or form

Zyloric 300

Common questions

What is Zyloric 100?

Zyloric 100 is a tablet by GSK containing Allopurinol 100 mg.

What is Zyloric 100 used for?

Lowers uric acid to prevent gout attacks and kidney stones.

How should I take Zyloric 100?

Usually 100 to 300 mg once a day after food, increased slowly; drink plenty of water. Gout flares can rise in the first months; your doctor may add colchicine. Always follow the dose your doctor or the pack gives.

What are the side effects of Zyloric 100?

Common side effects include: Rash, nausea, diarrhoea. Get medical help straight away for: Any rash, especially with fever, blisters or mouth sores (stop at once, higher risk in people of Han Chinese, Thai or Korean origin with HLA-B*5801).

Does Zyloric 100 need a prescription?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Can I take Zyloric 100 in pregnancy or while breastfeeding?

Not recommended in pregnancy or while breastfeeding.

What are the substitutes for Zyloric 100?

Brands with the same composition: Ciploric 100. Ask your doctor or pharmacist before switching.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.