Allopurinol

Gout preventer
PRESCRIPTION ONLY IN INDIA

Allopurinol is a gout preventer found in 3 medicines sold in India, such as Zyloric 100, Ciploric 100, Zyloric 300. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

What it is used for

Lowers uric acid to prevent gout attacks and kidney stones.

How it works

Reduces uric acid production, preventing gout attacks and some kidney stones.

How to take it

Usually 100 to 300 mg once a day after food, increased slowly; drink plenty of water. Gout flares can rise in the first months; your doctor may add colchicine.

Common side effects

  • Rash
  • Nausea
  • Diarrhoea

Get medical help straight away if

  • Any rash, especially with fever, blisters or mouth sores (stop at once
  • Higher risk in people of Han Chinese, Thai or Korean origin with HLA-B*5801)

Be careful

Do not start during an attack; stop and see a doctor if a rash appears.

Other medicines and interactions

Greatly raises azathioprine and mercaptopurine levels. Raises warfarin effect slightly.

Pregnancy and breastfeeding

Not recommended in pregnancy or while breastfeeding.

Brands of Allopurinol (3)

Ciploric 100Zyloric 100Zyloric 300

Common questions

What is Allopurinol used for?

Lowers uric acid to prevent gout attacks and kidney stones.

How does Allopurinol work?

Reduces uric acid production, preventing gout attacks and some kidney stones.

How should I take Allopurinol?

Usually 100 to 300 mg once a day after food, increased slowly; drink plenty of water. Gout flares can rise in the first months; your doctor may add colchicine.

What are the side effects of Allopurinol?

Common: Rash, nausea, diarrhoea. Get help straight away for: Any rash, especially with fever, blisters or mouth sores (stop at once, higher risk in people of Han Chinese, Thai or Korean origin with HLA-B*5801).

Does Allopurinol interact with other medicines?

Greatly raises azathioprine and mercaptopurine levels. Raises warfarin effect slightly.

Is Allopurinol safe in pregnancy and breastfeeding?

Not recommended in pregnancy or while breastfeeding.

Does Allopurinol need a prescription in India?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Which brands contain Allopurinol?

Ciploric 100, Zyloric 100, Zyloric 300.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.