Zyloric 300
Zyloric 300 is a tablet made by GSK that contains Allopurinol 300 mg. Allopurinol is a gout preventer: lowers uric acid to prevent gout attacks and kidney stones.
| Ingredient (salt) | Amount |
|---|---|
| Allopurinol | 300 mg |
What it is used for
Lowers uric acid to prevent gout attacks and kidney stones.
How it works
Reduces uric acid production, preventing gout attacks and some kidney stones.
How to take it
Usually 100 to 300 mg once a day after food, increased slowly; drink plenty of water. Gout flares can rise in the first months; your doctor may add colchicine.
Common side effects
- Rash
- Nausea
- Diarrhoea
Get medical help straight away if
- Any rash, especially with fever, blisters or mouth sores (stop at once
- Higher risk in people of Han Chinese, Thai or Korean origin with HLA-B*5801)
Be careful
Do not start during an attack; stop and see a doctor if a rash appears.
Other medicines and interactions
Greatly raises azathioprine and mercaptopurine levels. Raises warfarin effect slightly.
Pregnancy and breastfeeding
Not recommended in pregnancy or while breastfeeding.
Same ingredients, different strength or form
Common questions
What is Zyloric 300?
Zyloric 300 is a tablet by GSK containing Allopurinol 300 mg.
What is Zyloric 300 used for?
Lowers uric acid to prevent gout attacks and kidney stones.
How should I take Zyloric 300?
Usually 100 to 300 mg once a day after food, increased slowly; drink plenty of water. Gout flares can rise in the first months; your doctor may add colchicine. Always follow the dose your doctor or the pack gives.
What are the side effects of Zyloric 300?
Common side effects include: Rash, nausea, diarrhoea. Get medical help straight away for: Any rash, especially with fever, blisters or mouth sores (stop at once, higher risk in people of Han Chinese, Thai or Korean origin with HLA-B*5801).
Does Zyloric 300 need a prescription?
Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.
Can I take Zyloric 300 in pregnancy or while breastfeeding?
Not recommended in pregnancy or while breastfeeding.
What are the substitutes for Zyloric 300?
We have no other brand with exactly the same composition and strength in our list yet. Ask your pharmacist for an equivalent.
Sources and further reading
- Allopurinol: NHS · MedlinePlus
NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.
Composition checked against pack details from large Indian online pharmacies. Last reviewed 31 October 2026. Written by Satya Babu.
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