Glimepiride

Diabetes medicine (sulfonylurea)
PRESCRIPTION ONLY IN INDIA

Glimepiride is a diabetes medicine (sulfonylurea) found in 50 medicines sold in India, such as Amaryl 1, Azulix 1, Amaryl 2. Below: what it is for, how it works, how to take it, side effects, interactions and pregnancy advice.

What it is used for

Lowers blood sugar by making the pancreas release more insulin.

How it works

A sulfonylurea that makes the pancreas release more insulin, lowering blood sugar.

How to take it

Usually 1 to 4 mg once a day with breakfast or the first main meal. Do not skip meals after taking it.

Common side effects

  • Low blood sugar
  • Weight gain
  • Nausea

Get medical help straight away if

  • Low blood sugar: shaking, sweating, hunger, confusion or fainting (take 15 g of sugar such as glucose or juice, then food)
  • Yellow skin
  • Rash

Be careful

Can cause low sugar (shaking, sweating); do not skip meals.

Other medicines and interactions

Low sugar is more likely with alcohol, other diabetes medicines, fluconazole, some antibiotics (clarithromycin, quinolones) and beta blockers, which can also hide the warning signs.

Pregnancy and breastfeeding

Usually switched to insulin in pregnancy. Not recommended while breastfeeding.

Brands of Glimepiride (26)

Amaryl 1Amaryl 2Azulix 1Azulix 2Diapride 1Diapride 2Euglim 1Euglim 2Geminor 1Gepride 1Glador 1Glador 2Glimda 2Glimer 2Glimestar 1Glimestar 2Glimiprex 1Glimisave 1Glimisave 2Glimy 2Glypride 1Glyree 1GP 1GP-2Zoryl 1Zoryl-2

Combination medicines that contain Glimepiride (24)

Amaryl M 1Amaryl M 2Azulix 1 MFDiapride M 1Gemer 1Gemer 2Geminor M1Glador M1Glimestar-M 1Glimestar-M 2Glimisave-M 1Glimisave-M 2Glimy MGluconorm-G 1Gluconorm-G 2Glucoryl-M1Gluformin G 1Glyciphage-G 1Glycomet Trio 2/0.3Glycomet-GP 0.5Glycomet-GP 1Glycomet-GP 2Zoryl-M 1Zoryl-M 2

Common questions

What is Glimepiride used for?

Lowers blood sugar by making the pancreas release more insulin.

How does Glimepiride work?

A sulfonylurea that makes the pancreas release more insulin, lowering blood sugar.

How should I take Glimepiride?

Usually 1 to 4 mg once a day with breakfast or the first main meal. Do not skip meals after taking it.

What are the side effects of Glimepiride?

Common: Low blood sugar, weight gain, nausea. Get help straight away for: Low blood sugar: shaking, sweating, hunger, confusion or fainting (take 15 g of sugar such as glucose or juice, then food), yellow skin, rash.

Does Glimepiride interact with other medicines?

Low sugar is more likely with alcohol, other diabetes medicines, fluconazole, some antibiotics (clarithromycin, quinolones) and beta blockers, which can also hide the warning signs.

Is Glimepiride safe in pregnancy and breastfeeding?

Usually switched to insulin in pregnancy. Not recommended while breastfeeding.

Does Glimepiride need a prescription in India?

Yes. In India it is a prescription (Schedule H) medicine, so a pharmacist should sell it only with a doctor's prescription.

Which brands contain Glimepiride?

Amaryl 1, Amaryl 2, Amaryl M 1, Amaryl M 2, Azulix 1, Azulix 1 MF, Azulix 2, Diapride 1, Diapride 2, Diapride M 1, Euglim 1, Euglim 2, Gemer 1, Gemer 2, Geminor 1, Geminor M1, Gepride 1, Glador 1, Glador 2, Glador M1, Glimda 2, Glimer 2, Glimestar 1, Glimestar 2, Glimestar-M 1 and 25 more.

Sources and further reading

NHS (UK National Health Service) and MedlinePlus (US National Library of Medicine) are free, reviewed medicine guides. Brand names and doses there may differ from India.

Last reviewed 31 October 2026. Written by Satya Babu from standard prescribing information.

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For information only, not medical advice. This page is a plain-language summary written from standard prescribing information and the public guides linked below. Brands sometimes change their formula, so always check the composition printed on the pack. Doses here are typical adult doses; yours may differ. Do not start, stop or change a medicine without your doctor or pharmacist, and keep all medicines away from children. In an emergency, call 112 (India) or your local emergency number.