Joints and bones
Hyaluronic acid
Also called: hyaluronan, sodium hyaluronate
A substance in joint fluid and skin.
- Why people take it
- Joints, skin.
- What the evidence says
- Limited evidence by mouth; injections are used for knees by doctors.
- How it is usually taken
- Usually 80 to 200 mg a day by mouth; injections into the knee are a medical procedure.
- Be careful
- Generally safe.
- Medicines it can interact with
- No important medicine interactions are known, but tell your doctor and pharmacist about every supplement you take.
Other joints and bones
Common questions
What is Hyaluronic acid?
A substance in joint fluid and skin.
Why do people take Hyaluronic acid?
Joints, skin.
Does Hyaluronic acid work?
Limited evidence by mouth; injections are used for knees by doctors.
How much Hyaluronic acid do people take?
Usually 80 to 200 mg a day by mouth; injections into the knee are a medical procedure.
Is Hyaluronic acid safe?
Generally safe.
Does Hyaluronic acid interact with medicines?
No important medicine interactions are known, but tell your doctor and pharmacist about every supplement you take.
Sources and further reading
Last reviewed 31 October 2026. Written by Satya Babu.
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