Joints and bones

Undenatured type II collagen

Also called: UC-II

A chicken cartilage collagen.

Why people take it
Osteoarthritis.
What the evidence says
A few small studies.
How it is usually taken
Usually 40 mg a day.
Be careful
Generally safe.
Medicines it can interact with
No important medicine interactions are known, but tell your doctor and pharmacist about every supplement you take.

Other joints and bones

Common questions

What is Undenatured type II collagen?

A chicken cartilage collagen.

Why do people take Undenatured type II collagen?

Osteoarthritis.

Does Undenatured type II collagen work?

A few small studies.

How much Undenatured type II collagen do people take?

Usually 40 mg a day.

Is Undenatured type II collagen safe?

Generally safe.

Does Undenatured type II collagen interact with medicines?

No important medicine interactions are known, but tell your doctor and pharmacist about every supplement you take.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. Supplements are not medicines: they are not tested and approved like drugs before they are sold, and they can interact with medicines. Talk to your doctor or pharmacist before you start one, especially if you are pregnant or breastfeeding, take regular medicines, or have kidney, liver or heart disease.