Minerals

Lithium orotate

Also called: lithium

A low-dose form of lithium sold as a supplement.

Why people take it
Mood.
What the evidence says
Not well studied as a supplement; prescription lithium is a medicine that needs blood tests.
How it is usually taken
Sold in low doses of 1 to 5 mg elemental lithium; not tested like prescription lithium.
Be careful
Can affect the thyroid and kidneys and interacts with many medicines. Do not use without a doctor.
Medicines it can interact with
Must not be combined with prescription lithium; diuretics, ACE inhibitors, ARBs and NSAIDs raise lithium levels.

Other minerals

Common questions

What is Lithium orotate?

A low-dose form of lithium sold as a supplement.

Why do people take Lithium orotate?

Mood.

Does Lithium orotate work?

Not well studied as a supplement; prescription lithium is a medicine that needs blood tests.

How much Lithium orotate do people take?

Sold in low doses of 1 to 5 mg elemental lithium; not tested like prescription lithium.

Is Lithium orotate safe?

Can affect the thyroid and kidneys and interacts with many medicines. Do not use without a doctor.

Does Lithium orotate interact with medicines?

Must not be combined with prescription lithium; diuretics, ACE inhibitors, ARBs and NSAIDs raise lithium levels.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. Supplements are not medicines: they are not tested and approved like drugs before they are sold, and they can interact with medicines. Talk to your doctor or pharmacist before you start one, especially if you are pregnant or breastfeeding, take regular medicines, or have kidney, liver or heart disease.