Fats and oils

Phosphatidylserine

Also called: PS

A fat found in brain cell membranes.

Why people take it
Memory, stress.
What the evidence says
Weak evidence.
How it is usually taken
Usually 100 mg three times a day.
Be careful
May add to blood thinners.
Medicines it can interact with
May add to blood thinners and some dementia medicines.

Other fats and oils

Common questions

What is Phosphatidylserine?

A fat found in brain cell membranes.

Why do people take Phosphatidylserine?

Memory, stress.

Does Phosphatidylserine work?

Weak evidence.

How much Phosphatidylserine do people take?

Usually 100 mg three times a day.

Is Phosphatidylserine safe?

May add to blood thinners.

Does Phosphatidylserine interact with medicines?

May add to blood thinners and some dementia medicines.

Sources and further reading

Last reviewed 31 October 2026. Written by Satya Babu.

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For information only, not medical advice. Supplements are not medicines: they are not tested and approved like drugs before they are sold, and they can interact with medicines. Talk to your doctor or pharmacist before you start one, especially if you are pregnant or breastfeeding, take regular medicines, or have kidney, liver or heart disease.